Lipid formulations for oral administration of drugs: non-emulsifying, self-emulsifying and 'self-microemulsifying' drug delivery systems.
By Colin W. Pouton. European Journal of Pharmaceutical Sciences, 2000
1,207 citations recorded by the source corpus.
Subfields: Pharmaceutical Science
View Paper: https://www.semanticscholar.org/paper/5f9920ab311fa88d59b5a2e43e75c6392d5078f3
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In Pharmaceutical Science
- Christopher J. H. Porter
- W. Charman
- Natalie L. Trevaskis
- E. Merisko-Liversidge
- G. Liversidge
- Raviraj M. Kulkarni
- A. Date
- V. Patravale
Citations in the corpus
- Drug Nanoparticles: Formulating Poorly Water-Soluble Compounds (2008, background): “The approaches can be viewed as being a building-up approach through synthesis (Liu and Frechet, 1999), self-assembly (Letchford and Burt, 2007; Kawakami et al., 2002; Pouton, 2000), or precipitation of drug molecules (Horn and Rieger, 2001).”
- Strategies to Address Low Drug Solubility in Discovery and Development (2013, neutral): “Pouton (2000) introduced the Lipid Formulation Classification System (LFCS) in 2000 to describe and classify LBF according to their composition and behavior on dispersion and digestion.”
- Nanosuspensions: a promising drug delivery strategy (2004, background): “The problem is even more intense for drugs such as itraconazole and carbamazepine (belonging to class III as classified by Washington 1996), as they are poorly soluble in both aqueous and organic media, and for drugs having a log P value of 2 (Pouton 2000).”
- Development of nanoparticles for antimicrobial drug delivery. (2010, background): “In addition to topical applications, SLNs in the forms of tablets, capsules and pellets can also be used for oral administration[57].”
- Lipids and lipid-based formulations: optimizing the oral delivery of lipophilic drugs (2007, background): “Second, several studies have suggested that highly dispersed formulations — and in particular those that self emulsify on contact with GI fluids to provide submicron sized particles ('self-microemulsifying' formulations) — provide for enhanced bioavailability (reviewed in Ref”