Drug Nanoparticles: Formulating Poorly Water-Soluble Compounds

By E. Merisko-Liversidge, G. Liversidge. Toxicologic pathology (Print), 2008

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Strategies to Address Low Drug Solubility in Discovery and Development (2013, background): “…incorporate readily into tablet and capsule formulations and to use the same technology to generate simple oral suspension formulations for preclinical pharmacokinetic, efficacy, and toxicity studies (Merisko-Liversidge et al., 1996; Langguth et al., 2005; Merisko-Liversidge and Liversidge, 2008).”
Mesoporous silica nanoparticles in medicine--recent advances. (2013, background): “As more than 40% of substances discovered through combinatorial screening programs have poor solubility in water [49] it comes to no surprise that MSNs have attracted a high interest as drug carriers.”
Sol-gel based materials for biomedical applications (2016, background): “As more than 40% of substances discovered through combinatorial screening programs have poor solubility in water [523] it comes as no surprise that MSNs based materials have attracted a high interest as drug carriers.”