Development of nanoparticles for antimicrobial drug delivery.

By Liangfang Zhang, D. Pornpattananangku, C. J. Hu, Chun-Ming Huang. Current Medicinal Chemistry, 2010

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Advanced Materials and Processing for Drug Delivery: The Past and the Future (2012, background): “to $121 billion in 2010 [3]; the annual worldwide market for polymer-based controlled release system alone is estimated to be $60 billion in 2010 [4].”
The antimicrobial activity of nanoparticles: present situation and prospects for the future (2017, background): “34 This section focuses on the distinct features and complementary advantages of using NPs/nanotechnologies as antibacterial agents compared with traditional antibiotics, which can be summarized as follows: 1) overcoming the existing antibiotic resistance mechanisms that are listed in the…”
Alternative Antimicrobial Approach: Nano-Antimicrobial Materials (2015, neutral): “This includes combattingmultidrug-resistantmutants and biofilm [7, 8].”
Nanotechnology as a therapeutic tool to combat microbial resistance. (2013, background): “Each of these bilayers contains amphipathic lipid, often phosphatidylcholine, and commonly includes cholesterol in order to increase rigidity of the membrane [10,12].”
Antimicrobial Peptides: An Emerging Category of Therapeutic Agents (2016, background): “…of formulations for local delivery to specific tissues and, by controlling degradation of the carrier, allow time-controlled release of the peptides, in addition to improving metabolic as well as chemical stability of the AMPs (Zhang et al., 2010; Witting et al., 2015; Sandreschi et al., 2016).”