Exosomes: current knowledge of their composition, biological functions, and diagnostic and therapeutic potentials.
By A. Vlassov, S. Magdaleno, R. Setterquist, Rick Conrad. Biochimica et Biophysica Acta, 2012
1,845 citations recorded by the source corpus.
Subfields: Molecular Biology, Obstetrics and Gynecology, Public Health, Environmental and Occupational Health
View Paper: https://www.semanticscholar.org/paper/8106d494de6d5f45e7008d5f62ab714303745647
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In Molecular Biology
Citations in the corpus
- Standardization of sample collection, isolation and analysis methods in extracellular vesicle research (2013, neutral): “Biofluids EV are present in biological fluids (31,32).”
- Isolation of Extracellular Vesicles: General Methodologies and Latest Trends (2018, background): “Theoretically, each exosome along with the listed lipids can contain ≤100 proteins and ≤10,000 net nucleotides of nucleic acid [21].”
- Exosomes: vehicles of intercellular signaling, biomarkers, and vectors of cell therapy. (2015, background): “tion, endosomes contain proteins involved in lipid metabolism (40) (Figure 3).”
- Manufacturing Exosomes: A Promising Therapeutic Platform. (2018, neutral): “During this process, exosomes are loaded with various types of bioactive cargo (Figure 1), comprising protein and RNA molecules (including mRNA and miRNA) [5].”
- Exosomes Derived from Mesenchymal Stem Cells (2014, background): “The most unique function of exosomes might be specific interactions with targeted recipient cells, which putatively enables cell-to-cell communication between widely separated locations in the body [32].”
- Bovine milk-derived exosomes for drug delivery (2015, methodology): “Nevertheless, these physical and molecular attributes were in accordance with reports for classification of the secreted vesicle as exosomes [11, 31].”
- Targeting cancer stem cell pathways for cancer therapy (2020, background): “521 Exosomes contain a large number of functional proteins, RNA, microRNAs, DNA fragments, and other bioactive substances.”
- Innovative approaches for cancer treatment: current perspectives and new challenges (2019, background): “Specifically, exosomes are small vesicles of around 30–150 nm originated from endosomes in physiological and pathological conditions and released by a fusion of multivesicular bodies (MVBs) to the cell membrane [55, 56], while shed microvesicles (sMVs), with a typical size of 50–1,300 nm, are presen”
- Mesenchymal Stem Cell Exosomes Induce Proliferation and Migration of Normal and Chronic Wound Fibroblasts, and Enhance Angiogenesis In Vitro (2015, background): “Exosomes are small membrane-bound vesicles (diameter 30–120 nm), are secreted by a myriad of cells types and found in essentially all biological fluids, and originate from inward budding of late endosomes with resultant multivesicular bodies that are fused with the plasma membrane [20,21].”