Modulation of hypoxia-inducible factor 1alpha expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: implications for tumor…

By H. Zhong, K. Chiles, D. Feldser, E. Laughner, C. Hanrahan, M. Georgescu, J. Simons, G. Semenza. Cancer Research, 2000

1,562 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/5ed87a8f033f8308ec7d65dd9a5954490c500da8

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

1. G. Semenza
2. David M. Sabatini
3. C. Wigerup
4. B. Manning
5. M. C. Simon
6. M. Laplante
7. B. Keith
8. M. V. Vander Heiden

Citations in the corpus

• Regulation of Hypoxia-Inducible Factor 1α Expression and Function by the Mammalian Target of Rapamycin (2002, background): “These results are in general agreement with those reported by Zhong et al., who observed that rapamycin exposure inhibited epidermal growth factor and phorbol myristate acetate-induced secretion of VEGF, a HIF-1-regulated gene product, from TSU prostate cancer cells ( 50 ).”
• The role of oxygen availability in embryonic development and stem cell function (2008, background): “; furthermore, HIF-α protein expression is dependent on mTOR in some cellular context”