The Biogenesis and Functions of Exosomes
By W. Stoorvogel, M. Kleijmeer, H. Geuze, G. Raposo. Traffic : the International Journal of Intracellular Transport, 2002
849 citations recorded by the source corpus.
Subfields: Immunology, Molecular Biology
View Paper: https://www.semanticscholar.org/paper/5dae312c87f5c527687281286442935d42a1662c
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Immunology
- Richard J. Simpson
- G. Raposo
- Suresh Mathivanan
- W. Stoorvogel
- Benoît Février
- Arnold J. Levine
- J. Villadangos
- Bin Zhang
In Molecular Biology
- Suresh Mathivanan
- Richard J. Simpson
- Hina Kalra
- G. Raposo
- David W. Greening
- C. Théry
- W. Stoorvogel
- P. Altevogt
Citations in the corpus
- Deep sequencing of RNA from immune cell-derived vesicles uncovers the selective incorporation of small non-coding RNA biotypes with potential regulatory functions (2012, background): “Fusion of MVBs with the plasma membrane causes the release of their intraluminal vesicles, which are then called exosomes (7).”
- Exosomes: endosomal-derived vesicles shipping extracellular messages. (2004, background): “13 g/ml, but this may vary from cell to cell depending on the exosome protein content [15].”
- The regulation of exosome secretion: a novel function of the p53 protein. (2006, background): “lysosome, resulting in protein degradation, or alternatively, multivesicular bodies may fuse with the plasma membrane, thus, releasing cargo-loaded small vesicles into the extracellular space (16).”
- Cross‐presentation, dendritic cell subsets, and the generation of immunity to cellular antigens (2004, background): “Exosomes, which are small membrane-encased vesicles released by many cell types (56), have been reported to act as a source of cross-presented antigens (45, 46) and in some cases of whole peptide-loaded MHC molecules (56).”
- High Levels of Exosomes Expressing CD63 and Caveolin-1 in Plasma of Melanoma Patients (2009, background): “Exosomes are small endosome-derived vesicles (50–100 nm in size), actively secreted through an exocytosis pathway normally used for receptor discharge and intercellular cross-talk [1–3].”
- Mesenchymal stem cell: an efficient mass producer of exosomes for drug delivery. (2013, background): “For example, exosomes released frommaturing reticulocytes are rich in transferrin receptors that the reticulocytes have to dispose of while those from lymphocytes and dendritic cells have few transferrin receptors [23,56,57].”
- Cellular stress conditions are reflected in the protein and RNA content of endothelial cell-derived exosomes (2012, background): “E xosomes are small, spherical vesicles that are secreted upon fusion of the limiting membrane of multivesicular bodies with the plasma membrane (1,2).”
- Cellular Internalization of Exosomes Occurs Through Phagocytosis (2010, background): “or other related fluorescence techniques for this are still lacking (29,31).”
- Body fluid derived exosomes as a novel template for clinical diagnostics (2011, background): “They accumulate in cytosolic multivesicular bodies (MVBs) from where they are released by fusion with the plasma membrane [4,5].”