An alternative, nonapoptotic form of programmed cell death.

By S. Sperandio, I. Belle, D. Bredesen. Proceedings of the National Academy of Sciences of the United States of America, 2000

1,006 citations recorded by the source corpus.

Subfields: Molecular Biology

View Paper: https://www.semanticscholar.org/paper/4dc355e441a9d658ca589c93397ba1e6f6ef866d

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In Molecular Biology

1. S. Fink
2. B. Cookson
3. C. Brussaard
4. Susan A. Elmore
5. Nektarios Tavernarakis
6. J. Brugge
7. Jayanta Debnath
8. W. Dauer

Citations in the corpus

• What is the role and nature of programmed cell death in phytoplankton ecology? (2006, background): “carterae shows greatest morphological similarity with paraptosis (see Table 1 ) – an alternative outcome of PCD (Sperandio et al , 2000 ), which was originally observed in mammalian nerve tissue.”
• Classification of cell death (2005, neutral): “This term was originally introduced to describe a form of PCD morphologically and biochemically distinct from apoptosis.(71) In multiple cell types, paraptosis was triggered by the expression of the insulin-like growth factor receptor I, and it was associated with extensive cytoplasmic vacuolization”
• Death by necrosis (2002, background): “For example, alternative morphological death profiles such as paraptosis have been described (Clarke, 1990; Sperandio et al., 2000) and certain dying cells are known to exhibit some, but not all, commonly distinctive features of either apoptosis or necrosis.”
• The role of apoptosis in creating and maintaining luminal space within normal and oncogene-expressing mammary acini. (2002, background): “(Bursch et al., 2000; such as Bad, the transcriptional repression of proapoptotic genes, and improved glucose metabolism andLeist and Jaattela, 2001; Sperandio et al., 2000).”
• Apoptosis: A Review of Programmed Cell Death (2007, background): “However, it is important to note that other forms of programmed cell death have been described and other forms of programmed cell death may yet be discovered (Formigli et al., 2000; Sperandio et al., 2000; Debnath et al., 2005).”
• Neuronal Cell Death. (2018, neutral): “(641) defined “paraptosis” as a form of cell death, distinct from apoptosis and necrosis, characterized by cytoplasmic vacuolation.”
• Parkinson's Disease Mechanisms and Models (2003, background): “In addition, there may be nonapoptotic to mitochondrial damage and further production of ROS. forms of PCD (Clarke, 1999; Sperandio et al., 2000).”
• Apoptosis, Pyroptosis, and Necrosis: Mechanistic Description of Dead and Dying Eukaryotic Cells (2005, background): “In addition to those we have discussed here, other cell death programs including paraptosis are being described (14, 121, 122).”