Apoptosis: A Review of Programmed Cell Death

By Susan A. Elmore. Toxicologic pathology (Print), 2007

13,334 citations recorded by the source corpus.

Subfields: Epidemiology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/80aa42971b4125cd1f91b6e611e5cc858365ef96

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Citations in the corpus

The MTT Assay: Utility, Limitations, Pitfalls, and Interpretation in Bulk and Single-Cell Analysis (2021, result): “However, cell death is a staged process usually taking a few hours to complete [59] and cells with a round shape could be at different stages of cell death, where at earlier stages, they still show some level of metabolic and enzymatic activity and could reduce MTT as shown by formazan formation in ”
Unexpected low‐dose toxicity of the universal solvent DMSO (2014, methodology): “AIF and PARP-1 activation have been previously implicated in caspase-independent cell death, through a newly proposed pathway of cell death: Parthanatos (65, 66).”
Lipid Peroxidation: Production, Metabolism, and Signaling Mechanisms of Malondialdehyde and 4-Hydroxy-2-Nonenal (2014, background): “The execution pathway results in characteristic cytomorphological features including cell shrinkage, chromatin condensation, formation of cytoplasmic blebs and apoptotic bodies, and finally phagocytosis of the apoptotic bodies by adjacent parenchymal cells, neoplastic cells or macrophages [352, 353]”
Zinc oxide nanoparticles induce oxidative DNA damage and ROS-triggered mitochondria mediated apoptosis in human liver cells (HepG2) (2012, background): “Another key event in the intrinsic pathway is disruption of the mitochondrial transmembrane potential which results in the release of pro-apoptotic factors activating the caspase cascade [47].”
Apoptosis and Molecular Targeting Therapy in Cancer (2014, background): “That will directly sequester the Fas ligand or expression of Fas ligand on the surface of tumor cells (reviewed, [36]).”
Apoptosis and acute kidney injury. (2011, background): “metry, cell shrinkage with ‘rounding’, cell detachment, chromosomal DNA fragmentation, chromatin condensation, and surface expression of opsonic receptors that allow neighboring cells to rapidly phagocytose membrane-bound chromatin fragments referred to as ‘apoptotic bodies’.(26) These morphologic c”
Cullin3-based polyubiquitination and p62-dependent aggregation of caspase-8 mediate extrinsic apoptosis signaling. (2009, neutral): “Apoptosis plays important roles in embryonic development and adult tissue maintenance, and its aberration contributes to cancer as well as to neurodegenerative and autoimmune diseases (Elmore, 2007; Hanahan and Weinberg, 2000).”
Fast Neural Architecture Construction using EnvelopeNets (2018, background): “Brain development is believed to consist of neurogenesis (29), where the neural structure initially develops, gradually followed by apoptosis (9), where neural cells are eliminated, introduction of more neurons by hippocampal neurogenesis (11) and synaptic pruning (17), where synapses are eliminated”
Combination therapy in combating cancer (2017, background): “These death receptors trigger intracellular signaling that results in the cleaving and activation of caspases such as caspase-3 and caspase-8, which ultimately lead to apoptosis [165, 166].”