Dietary agents in cancer prevention: flavonoids and isoflavonoids.

By D. Birt, S. Hendrich, Weiqun Wang. Pharmacology and Therapeutics, 2001

1,174 citations recorded by the source corpus.

Subfields: Biochemistry, Pathology and Forensic Medicine

View Paper: https://www.semanticscholar.org/paper/4b7ab7ca5aaad9b06dfa3b7dc5a779730a046ba1

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Biochemistry

1. F. Tomás-Barberán
2. G. Williamson
3. Eboh Abraham Sisein

In Pathology and Forensic Medicine

1. F. Tomás-Barberán
2. R. Masella
3. G. Williamson

Citations in the corpus

• Flavonoids: Promising anticancer agents (2003, background): “effects and can be considered possible chemopreventive or therapeutic agents against cancer.(17,18) This review article will focus on the anticancer activity of flavonoids as well as their molecular mechanisms, since they are among the most promising anticancer agents.”
• Deglycosylation by small intestinal epithelial cell β-glucosidases is a critical step in the absorption and metabolism of dietary flavonoid glycosides in humans (2003, background): “However it is not known if these anti-carcinogenic properties are directly and/or entirely due to their antioxidant properties (see [ 12 ]).”
• Luteolin, a flavonoid, as an anticancer agent: A review. (2019, background): “tric, prostate and melanoma, luteolin exhibits cell cycle arrest during the G1 phase, whereas G1 cell cycle arrest induced by luteolin is linked to suppression of the CDK2 activity in colorectal cancer HT-29 and melanoma OCM-1 cells [12,13].”
• Luteolin, a flavonoid with potential for cancer prevention and therapy. (2008, background): “nutrients that are antioxidants, estrogenic regulators, and antimicrobial agents [2].”
• Flavonoids in Food and Their Health Benefits (2004, background): “They contain conjugated ring structures and hydroxyl groups that have the potential to function as antioxidants in vitro or cell free systems by scavenging superoxide anion, singlet oxygen, lipid peroxyradicals, and stabilizing free radicals involved in oxidative processes through hydrogenation or c”
• Novel mechanisms of natural antioxidant compounds in biological systems: involvement of glutathione and glutathione-related enzymes. (2005, background): “Polyphenols may also interact with caspase-dependent pathways [71–73]; interfere with cyclin-dependent regulation of the cell cycle [74]; induce detoxifying enzymes [75]; enhance the production of vasodilating factors such as nitric oxide [76,77]; affect the platelet function [78]; compete with gluc”
• Flavonoids as anti-inflammatory agents: implications in cancer and cardiovascular disease (2009, background): “Several mechanisms of action have been identified for flavonoids chemoprevention, including estrogenic/antiestrogenic activity, antiproliferation, induction of cellcycle arrest or apoptosis, prevention of oxidation, induction of detoxification enzymes, regulation of the host immune system, anti-infl”
• Polyphenols, dietary sources and bioavailability. (2007, background): “It is mainly by virtue of these properties that they exert their protective effects and receive more and more attention as potential therapeutic agents against several chronic degenerative diseases [20, 21].”