Mitogen-activated protein kinases in synaptic plasticity and memory.

By J. Sweatt. Current Opinion in Neurobiology, 2004

1,059 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Developmental Neuroscience, Genetics

View Paper: https://www.semanticscholar.org/paper/464ce65c31d198fdde4ca0fef5e69fb37bf58be9

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cellular and Molecular Neuroscience

1. R. Malenka
2. A. Citri
3. C. Lüscher
4. Charles R. Gerfen
5. D. Surmeier
6. R. J. Kelleher
7. Y. Shaham
8. A. Goldin

In Developmental Neuroscience

1. Mark F. Bear
2. Y. Shaham
3. F. Theberge
4. B. Hope
5. Charles R. Gerfen
6. R. Malenka
7. C. Lüscher
8. A. Citri

In Genetics

1. R. J. Kelleher
2. Mark F. Bear
3. Y. Shaham
4. F. Theberge
5. B. Hope
6. Charles R. Gerfen
7. R. Malenka
8. C. Lüscher

Citations in the corpus

• The autistic neuron: troubled translation? (2008, background): “The ERK pathway, which is activated downstream of NMDAR, mGluR, and TrkB receptors, plays important roles in synaptic plasticity and memory (Sweatt, 2004).”
• Neurobiology of the incubation of drug craving (2011, positive): “ERK is a component of the mitogen-activated protein kinase (MAPK) intracellular signaling pathway and its activation plays an important role in synaptic plasticity mechanisms underlying learning and memory [59, 60].”
• Covalent modification of DNA regulates memory formation. (2007, neutral): “One upstream candidate regulator is ERK, which plays an integral role in hippocampal memory formation (Sweatt, 2004).”
• Transient Mitogen-Activated Protein Kinase Activation Is Confined to a Narrow Temporal Window Required for the Induction of Two-Trial Long-Term Memory in Aplysia (2007, background): “…of memory and synaptic plasticity on activation of signaling kinases such as mitogen-activated protein kinase (MAPK) that give rise to nuclear signaling and cAMP response elementbinding protein (CREB)-mediated transcription (Silva et al., 1998; Kandel, 2001; Sharma and Carew, 2004; Sweatt, 2004).”
• Plasticity in the human central nervous system. (2006, methodology): “…after hippocampus-dependent learning in mice and application of a MAPK inhibitor blocks the maintenance of LTP (Rosenblum et al., 2000; Rosenblum et al., 2002; Waltereit and Weller, 2003; Sweatt, 2004) and long-term memory formation (Atkins et al., 1998; Blum et al., 1999; Bozon et al., 2003).”
• BDNF is essential to promote persistence of long-term memory storage (2008, background): “BDNF promotes ERK activation and BDNF-induced LTP requires ERK activity (10, 20, 25).”
• TrkB signalling pathways in LTP and learning (2009, background): “The MAPK cascade that leads to activation of the ERK1–ERK2 pathway has also been suggested to be important for LTP and some forms of learning and memor”
• Modulation of striatal projection systems by dopamine (2011, positive): “Acting through PKA, D1 and A2a receptor activation leads to the phosphorylation of DARPP-32 and a variety of other signaling molecules, including MAPKs, linked to synaptic plasticity (Svenningsson et al., 2004; Sweatt, 2004).”
• NMDA receptor-dependent long-term potentiation and long-term depression (LTP/LTD). (2012, background): “…protein kinases, such as cAMP-dependent protein kinase (PKA), protein kinase C (PKC), mitogen-activated protein kinases, and tyrosine kinases, have all been suggested to contribute to LTP in various ways (Bliss and Collingridge 1993; Malenka and Nicoll 1999; Salter and Kalia 2004; Sweatt 2004).”
• Synaptic Plasticity: Multiple Forms, Functions, and Mechanisms (2008, background): “The extracellular signal-regulated kinase (Erk)/mitogen-activated protein kinase (MAPK) pathway has also been suggested to be important for LTP, as well as some forms of learning and memory (Sweatt, 2004; Thomas and Huganir, 2004).”