TrkB signalling pathways in LTP and learning

By L. Minichiello. Nature Reviews Neuroscience, 2009

1,064 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Developmental Neuroscience, Neurology

View Paper: https://www.semanticscholar.org/paper/b3a1a09d3d683aace7267e50a9408e04da60dff0

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cellular and Molecular Neuroscience

1. A. Watt
2. Niraj S. Desai
3. C. Duarte
4. Graciano Leal
5. Diogo Comprido
6. Andreas Meyer-Lindenberg
7. L. Colucci-D'Amato
8. E. T. Rolls

In Developmental Neuroscience

1. C. Duarte
2. Graciano Leal
3. Diogo Comprido
4. E. T. Rolls
5. Niraj S. Desai
6. Mu-Ming Poo
7. Marian Joëls
8. M. Millan

In Neurology

1. Andreas Meyer-Lindenberg
2. E. T. Rolls
3. Bruno Dubois
4. Niraj S. Desai
5. Mu-Ming Poo
6. C. Duarte
7. T. Jay
8. Marian Joëls

Citations in the corpus

• Frontiers in Synaptic Neuroscience Synaptic Neuroscience (positive): “Interestingly, BDNF is also implicated in LTP, where it is thought to be required for expression of the late, protein-dependent phase of LTP (Minichiello, 2009), or alternatively, synaptic tagging (Lu et al., 2008).”
• Cognitive dysfunction in psychiatric disorders: characteristics, causes and the quest for improved therapy (2012, background): “and the upstream driver of neurogenesis, BDNF, which acts via neurotrophic tyrosine kinase receptor type 2 (NTRK2; also known as TRKB”
• Neurotrophic Factor BDNF, Physiological Functions and Therapeutic Potential in Depression, Neurodegeneration and Brain Cancer (2020, background): “The PLC-γ-dependent pathway evokes activation of CAM kinase and protein kinase C (PKC), which subsequently increases the 1,2-diacylglycerol (DAG) and Ca2+ ion concentrations [89].”
• Neurotrophin regulation of neural circuit development and function (2012, background): “(PI3K)–AKT signalling enhances both local and global mRNA translation (10).”
• BDNF-induced local protein synthesis and synaptic plasticity. (2014, positive): “The neurotrophin brain-derived neurotrophic factor (BDNF) has been shown to play a key role asmediator of activity-induced LTP in the hippocampus as well as in other brain regions (Bramham and Messaoudi, 2005; Cowansage et al., 2010; Lu et al., 2008; Minichiello, 2009; Park and Poo, 2013; Santos et ”
• Structural and molecular remodeling of dendritic spine substructures during long-term potentiation (2014, result): “On the other hand, application of brain-derived neurotrophic factor (BDNF), known to trigger local translation and promote L-LTP (Minichiello, 2009), facilitated the spine enlargement, consistent with a previous report (Tanaka et al., 2008) and, concomitantly, enhanced and accelerated (to phases I…”
• BDNF: A Key Factor with Multipotent Impact on Brain Signaling and Synaptic Plasticity (2017, background): “…66 within the BDNF gene in the pro-domain encoding region 3-kinase (PI3K), mitogen-activated protein kinase (MAPK), phospholipase C-c (PLC-c), and guanosine triphosphate hydrolases (GTP-ases) of the Ras homolog (Rho) gene family (Gonzalez et al. 2016; Huang and Reichardt 2003; Minichiello 2009).”