The Genome Sequence of the Malaria Mosquito Anopheles gambiae

By R. Holt, G. Subramanian, A. Halpern, Granger G. Sutton, R. Charlab, D. Nusskern, P. Wincker, Andrew G. Clark, JoséM. C. Ribeiro, R. Wides and 113 more. Science, 2002

2,077 citations recorded by the source corpus.

Subfields: Immunology, Insect Science, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/43e94b605c04a2e7c6b3926f624c38921544148c

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Citations in the corpus

MAKER2: an annotation pipeline and genome-database management tool for second-generation genome projects (2011, positive): “melanogaster ESTs available from dbEST[26], and the protein homology input consisted of all Anopheles gambiae[27] proteins from NCBI together with all of the UniProt/Swiss-Prot[28,29] database proteins (minus Drosophila proteins).”
Genome evolution in yeasts (2004, background): “For example, two sequenced Diptera ( Anopheles gambiae”
A High Quality Draft Consensus Sequence of the Genome of a Heterozygous Grapevine Variety (2007, background): “Therefore, as shown for human [95], dog [94] and Anopheles [96] genomes, the Pinot Noir chromosomes consist of large blocks where two haplotypes are present.”
A deficit of detoxification enzymes: pesticide sensitivity and environmental response in the honeybee (2006, background): “Specifically there are only about half as many glutathioneS-transferases (GSTs), cytochrome P450 monooxygenases (P450s) and carboxyl/cholinesterases (CCEs) in the honeybee.”
The Repertoire of G-Protein–Coupled Receptors in Fully Sequenced Genomes (2005, background): “The genomic sequence of the mosquito A. gambiae was published as approximately 10 whole-genome shotgun in 2002 (Holt et al., 2002), and current assembly contains 278 Mbp in 18,634 contigs (http://www.ensembl.org/Anopheles_gambiae/).”
Reference sequence (RefSeq) database at NCBI: current status, taxonomic expansion, and functional annotation (2015, background): “This despite the fact that many species have critical biomedical importance such as Anopheles gambiae , a vector for malaria and Biomphalaria glabrata , a vector for schistosomiasis (34,35).”
The Ensembl automatic gene annotation system. (2004, methodology): “We also had to modify the gene build when analyzing Anopheles gambiae (Holt et al. 2002; Mongin et al. 2004); only a few gene families have been described, particularly those involved in odor reception and Plasmodium falciparum : Anopheles gambiae interactions , and as such there are few Anopheles…”
HiCanu: accurate assembly of segmental duplications, satellites, and allelic variants from high-fidelity long reads (2020, methodology): “The Overlap Error Adjustment (OEA) module (Holt et al. 2002; Koren et al. 2017) examines read overlap pileups to identify remaining sequencing errors in the individual reads and recomputes overlap alignment identities.”
Malaria: progress, perils, and prospects for eradication. (2008, positive): “Broad-based analyses of the genomes of vectors (130, 131) and pathogens, and the use of these new genomic data to better understand the complex population structure of natural vector populations, hold the key to long-term solutions.”
Metabolomics in pesticide research and development: review and future perspectives (2011, background): “However, the sequencing of insect genomes such as those of Drosophila melanogaster (Adams et al. 2000), Drosophila pseudoobscura (Richards, et al. 2005), and mosquito Anopheles gambiae (Holt et al. 2002) has been the turning point in the enrichment of our knowledge on the MOA of insecticides.”