The hallmarks of cancer.

By Douglas Hanahan, R. A. Weinberg. Cell, 2000

1,030 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/433546e496f7c9127f5f448623101f5f652d7850

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Citations in the corpus

The Science and Translation of Lactate Shuttle Theory. (2018, neutral): “The high glucose uptake/lactate release phenotype remains a hallmark of cancer (Hanahan and Weinberg, 2000; Koppenol et al., 2011), but today there is no consensus on the meaning of the observations.”
Membrane type I matrix metalloproteinase usurps tumor growth control imposed by the three-dimensional extracellular matrix. (2003, neutral): “of type I collagen or crosslinked fibrin (Hanahan and Weinberg, 2000; Hiraoka et al., 1998; Liotta and Kohn, 2001; Chambers et al., 2002).”
Oct4 expression in adult human stem cells: evidence in support of the stem cell theory of carcinogenesis. (2004, neutral): “Among some “hallmarks” of cancer cells ( 17 ) is the ability to have indefinite proliferative potential.”
Extracellular matrix: a dynamic niche component during cancer progression (2012, neutral): “These include the acquisition by cancer cells of the ability to survive, grow, and invade (Hanahan and Weinberg, 2000, 2011).”
Telomerase and cancer therapeutics (2008, neutral): “One of the important tumour escape mechanisms is telomerase activation to circumvent the telomere-dependent pathways of cell mortality: replicative senescence and crisis”
Mitochondria in cancer cells: what is so special about them? (2008, positive): “To date, there are six known essential alterations in cell physiology that collectively might dictate malignant transformation: self-sufficiency in growth signals, insensitivity to growth-inhibitory (antigrowth) signals, limitless replicative potential, sustained angiogenesis, tissue invasion and me”
MicroRNA Functions in Stress Responses (2010, neutral): “In turn, these miRNAs together Molecular Cell 40, October 22, 2010 ª2010 Elsevier Inc. 205 (A) miRNAs are first transcribed as primary transcripts (pri-miRNA), which fold into hairpin structures and are subsequently processed—first by Drosha in the nucleus and then by Dicer in the cytoplasm.”
Four faces of cellular senescence (2011, neutral): “Moreover, to form a lethal tumor, cancer cells must acquire a greatly expanded growth potential and ability to proliferate while expressing activated oncogenes (Hanahan and Weinberg, 2000), traits that are suppressed by the senescence program.”
Inflammation and cancer (2002, neutral): “Activation of angiogenic programmes represents a shift in the balance between pro- and anti-angiogenic factor”