Histone H2A variants H2AX and H2AZ.
By C. Redon, D. Pilch, E. Rogakou, O. Sedelnikova, K. Newrock, W. Bonner. Current Opinion in Genetics and Development, 2002
825 citations recorded by the source corpus.
Subfields: Molecular Biology
View Paper: https://www.semanticscholar.org/paper/3a237483449a9741717a1fb2759943bf2742c828
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Molecular Biology
Citations in the corpus
- H2AX is required for chromatin remodeling and inactivation of sex chromosomes in male mouse meiosis. (2003, background): “This is consistent with the requirement for H2AX to be availDNA double-strand breaks (DSBs) (Redon et al., 2002).”
- Structural and Functional Conservation of the NuA4 Histone Acetyltransferase Complex from Yeast to Humans (2004, methodology): “for nucleosomal HAT activity, full-length Tip60, Tip60b, ING3, ING3(1-300),”
- Topoisomerase I inhibitors: camptothecins and beyond (2006, neutral): “At the chromatin level, the H2AX histone variant, which represents 10–20% of histone H2”
- Controlling the double helix (2003, background): “Third, histone variants may replace one or more of the core histone”
- Genome-wide dynamics of Htz1, a histone H2A variant that poises repressed/basal promoters for activation through histone loss. (2005, neutral): “Studies in flies present a complex picture; the fly ortholog, termed H2AνD, appears to be a hybrid of two mammalian H2A variants ( Redon et al., 2002 ).”