H2AX is required for chromatin remodeling and inactivation of sex chromosomes in male mouse meiosis.
By O. Fernández-Capetillo, S. Mahadevaiah, Arkady Celeste, P. Romanienko, R. Camerini‐Otero, W. Bonner, K. Manova, P. Burgoyne, A. Nussenzweig. Developmental Cell, 2003
619 citations recorded by the source corpus.
Subfields: Genetics, Molecular Biology
View Paper: https://www.semanticscholar.org/paper/8e7fed2f7c0024ed3387d94e94bc07834f2a70ba
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In Genetics
- Hiroyuki Sasaki
- Yasuhisa Matsui
- D. Bourc’his
- T. Bestor
- Gregory J. Hannon
- Jian‐Kang Zhu
- Anne Ferguson-Smith
In Molecular Biology
- Gregory J. Hannon
- Hiroyuki Sasaki
- D. Bourc’his
- Yasuhisa Matsui
- T. Bestor
- M. Carmell
- Yi Zhang
- Jian‐Kang Zhu
Citations in the corpus
- Epigenetic events in mammalian germ-cell development: reprogramming and beyond (2008, background): “This form of X-chromosome inactivation is called meiotic sex-chromosome inactivation (MSCI) ( Figs 1 , 4 ), and might be necessary for synapsis of the pseudo-autosomal region”
- Meiotic sex chromosome inactivation (2007, neutral): “Mutations in genes required for MSCI, including H2ax (Fernandez-Capetillo et al., 2003) and Brca1 (Xu et al., 2003), cause meiotic arrest midway through pachytene; however, in these instances it is difficult to determine whether the primary cause of the meiotic arrest is due to MSCI failure, because”
- The X and Y Chromosomes Assemble into H2A.Z, Containing Facultative Heterochromatin, following Meiosis (2006, background): “4) (40) at a time when H2AX becomes phosphorylated (16, 60).”
- MIWI2 is essential for spermatogenesis and repression of transposons in the mouse male germline. (2007, background): “Consistent with this notion, LINE and IAP elements are known to be active almost exclusively in the germline (Branciforte and Martin, 1994; Dupressoir and Heidmann, 1996 ).”
- Histone variants — ancient wrap artists of the epigenome (2010, neutral): “X is also required for the remodelling and inactivation of the sex chromosomes in male mouse meiosis 84 , where it precedes the chromosome-wide deposition of H3.”