Genome-wide dynamics of Htz1, a histone H2A variant that poises repressed/basal promoters for activation through histone loss.
By Haiying Zhang, Douglas N. Roberts, B. Cairns. Cell, 2005
595 citations recorded by the source corpus.
Subfields: Molecular Biology, Plant Science
View Paper: https://www.semanticscholar.org/paper/32ffdb3ae1a5dd4adccb088388375e84f981ebb1
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Molecular Biology
- Steven Henikoff
- K. Zaret
- Cedric R Clapier
- Jerry L. Workman
- Jason S. Carroll
- Terri D. Bryson
- M. Carey
- Bing Li
In Plant Science
Citations in the corpus
- The role of chromatin during transcription. (2007, background): “Upon transcription activation, however, Htz1 is rapidly evicted from the promoter, and its loss is required for full transcription (Zanton and Pugh, 2006; Zhang et al., 2005).”
- Histone variants — ancient wrap artists of the epigenome (2010, unknown): “Z in reconstituted nucleosomes, yeast Htz1 nucleosomes in chromatin have high turnover rates in promoter regions 6 and are less stable to salt washes than H2A nucleosomes 67 .”
- H2A.Z-containing nucleosomes mediate the thermosensory response in Arabidopsis. (2010, unknown): “Z-containing nucleosomes are especially enriched at the +1 position near the transcriptional start site (Creyghton et al., 2008; Mavrich et al., 2008; Raisner et al., 2005; Whittle et al., 2008; Zhang et al., 2005; Zilberman et al., 2008).”
- Pioneer transcription factors: establishing competence for gene expression. (2011, background): “Z, at promoters can also destabilize nucleosomes (Zhang et al. 2005; Jin and Felsenfeld 2007; Jin et al. 2009).”
- The biology of chromatin remodeling complexes. (2009, background): “These nucleosomes may be less stable than canonical nucleosomes, facilitating promoter DNA exposure and activation (19, 115).”
- Dynamic regulation of nucleosome positioning in the human genome. (2008, unknown): “Z is highly enriched at yeast promoter regions (Guillemette et al., 2005; Zhang et al., 2005) and has been found to flank an NFR near the TSS (Raisner et al., 2005), suggesting a potential role for H2A.”
- Precise genome-wide mapping of single nucleosomes and linkers in vivo (2018, background): “Z is localized to the promoters of less active genes [76, 77], suggesting that during transcription, histone variant H2A.”