Metabolism of highly unsaturated n-3 and n-6 fatty acids.

By H. Sprecher. Biochimica et Biophysica Acta, 2000

900 citations recorded by the source corpus.

Subfields: Molecular Biology, Nutrition and Dietetics, Surgery

View Paper: https://www.semanticscholar.org/paper/370a3536c78964efc2660a12d3bf454e1d455dcc

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. J. Vance
2. S. Siriamornpun
3. G. Barceló-Coblijn
4. E. Murphy
5. D. Vance
6. D. Tocher
7. B. Torstensen
8. Ó. Monroig

In Nutrition and Dietetics

1. D. Tocher
2. S. Siriamornpun
3. G. Barceló-Coblijn
4. E. Murphy
5. J. Vance
6. D. Vance
7. Ó. Monroig
8. S. Wootton

In Surgery

1. S. Siriamornpun
2. G. Barceló-Coblijn
3. E. Murphy
4. J. Vance
5. D. Vance
6. D. Tocher
7. Ó. Monroig
8. S. Wootton

Citations in the corpus

• The key roles of elongases and desaturases in mammalian fatty acid metabolism: Insights from transgenic mice. (2010, background): “Biosynthesis VLC-PUFAs of the n 6 and n 3 series occurs via sequential desaturation, elongation [128] and partial degradation step [129].”
• Omega-3 long-chain polyunsaturated fatty acids and aquaculture in perspective (2015, background): “same Δ6 as in the EPA pathway), and peroxisomal chain shortening (Sprecher, 2000).”
• Alpha-linolenic acid and its conversion to longer chain n-3 fatty acids: benefits for human health and a role in maintaining tissue n-3 fatty acid levels. (2009, background): “22:5n 3 is elongated to 24:5n 3 [61,62].”
• Towards Fish Lipid Nutrigenomics: Current State and Prospects for Fin-Fish Aquaculture (2008, background): “Rather, EPA undergoes two rounds of elongation to form 24:5n-3, which then undergoes 6 desaturation ( 6*) to 24:6n-3 followed by a chain-shortening reaction in the peroxisomes to 22:6n-3 (Figure 2; Sprecher, 2000).”
• POLYUNSATURATED FATTY ACID CONTENT OF EDIBLE INSECTS IN THAILAND (2006, background): “In contrast, aquicolous insects possessed enzymes such as D5 desaturase and D6 desaturase, which may have contributed to the synthesis of long-chain PUFAs (Sprecher 2000; Sinclair et al. 2002).”
• Conversion of α-linolenic acid to eicosapentaenoic, docosapentaenoic and docosahexaenoic acids in young women (2002, background): “A pathway for conversion of ALNA to EPA and DHA has been identified in rats (Voss et al. 1991; reviewed in Sprecher, 2000).”