Alpha-linolenic acid and its conversion to longer chain n-3 fatty acids: benefits for human health and a role in maintaining tissue n-3 fatty acid levels.

By G. Barceló-Coblijn, E. Murphy. Progress in lipid research, 2009

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Long-chain omega-3 fatty acids and the brain: a review of the independent and shared effects of EPA, DPA and DHA (2015, background): “Although the short-chain omega-3 PUFAs, α-linolenic acid (ALA, 18:3n-3) and stearidonic acid (SDA, 18:4n-3) have shown potential health benefits (Barceló-Coblijn and Murphy, 2009; Whelan, 2009), these have yet to be sufficiently explored in the context of central nervous system (CNS) disorders, and…”
Beneficial Outcomes of Omega-6 and Omega-3 Polyunsaturated Fatty Acids on Human Health: An Update for 2021 (2021, background): “Increasing ALA intake may produce modest cardioprotection by lowering 619 total and LDL-cholesterol (relative to saturated fatty acids), maintaining endothelial func- 620 tion, and through antithrombotic and anti-inflammatory effects [196,197].”
Halophytes: Gourmet food with nutritional health benefits? (2017, background): “responsible for the elongation of n-6 FA); iii) it can reduce the levels of serum triglycerides; iv) its anti-inflammatory properties may help in the prevention of primary and secondary coronary artery disease by a different mechanism than that of EPA and DHA; and v) it may display a positive effect”
Omega-3 and omega-6 polyunsaturated fatty acids: Dietary sources, metabolism, and significance - A review. (2018, background): “It has been established that dietary LA and ALA play crucial roles in maintaining tissue n3 and n-6 LC-PUFAs levels [19].”