Exosomes are released by cultured cortical neurones.

By Julien Fauré, G. Lachenal, Magali Court, J. Hirrlinger, C. Chatellard-Causse, Béatrice Blot, Julien Grange, G. Schoehn, Y. Goldberg, Véronique Boyer and 4 more. Molecular and cellular neurosciences, 2006

897 citations recorded by the source corpus.

Subfields: Molecular Biology

View Paper: https://www.semanticscholar.org/paper/36fdce77f994cb3c5034da849c7b01fd8a2d0314

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Citations in the corpus

Exosomes: a common pathway for a specialized function. (2006, methodology): “The protein composition of exosomes purified from different sources, and in particular from cell culture supernatants of B lymphocytes, DCs, intestinal epithelial cells, Schwann cells and neurons, has been analyzed by proteomics, Facs, Western-blotting and immunocytochemistry at the electron microsc”
Cell-Produced α-Synuclein Is Secreted in a Calcium-Dependent Manner by Exosomes and Impacts Neuronal Survival (2010, background): “These results are in agreement with previous reports (Théry et al., 2002, 2006; Fauré et al., 2006; Vingtdeux et al., 2007; Yuyama et al., 2008).”
Mesenchymal stem cell: an efficient mass producer of exosomes for drug delivery. (2013, background): “T cell stimulation [23–25], tumor growth suppression [26], neurotransmission [27,28], myelinmembrane biogenesis [29], endothelial cellmigration [30] aswell as egg and sperm fusion [31].”
Extracellular vesicles: Exosomes, microvesicles, and friends (2013, background): “Similarly, plasma membrane depolarization increases the rapid secretion of exosomes by neuronal cells (Fauré et al., 2006; Lachenal et al., 2011), and cross-linking of CD3 in T cells stimulates exosome release by T cells (Blanchard et al.”
Biogenesis, secretion, and intercellular interactions of exosomes and other extracellular vesicles. (2014, background): “…to secrete exosomes in vitro, based on the presence of MVBs and the enrichment of MVB components in the secreted vesicles, including epithelial cells (Van Niel et al. 2001), neurons (Fauré et al. 2006), Schwann cells (Fevrier et al. 2004), and tumor cells (Wolfers et al. 2001), among others.”
Classification, Functions, and Clinical Relevance of Extracellular Vesicles (2012, background): “, 2010) or to lysosomes for degradation (Stenmark, 2009), as well as cytosolic calcium levels (Savina et al., 2003; Fauré et al., 2006; Krämer-Albers et al., 2007), citron kinase, (Loomis et al.”
Exosomes and microvesicles: extracellular vesicles for genetic information transfer and gene therapy. (2012, background): “For example, cortical neurone-derived exosomes transfer newly synthesized proteins including a-amino-3-hydroxy-5methyl-4-isoxazolepropionic acid receptor receptor subunits to the presynaptic terminals of connected neurones and contribute to the local synaptic plasticity (55,56).”
Exosomal cell-to-cell transmission of alpha synuclein oligomers (2012, background): “Exosome secretion can therefore be used by cells, including neurons and astrocytes, to clear molecules originally destined for lysosomal degradation [77].”