Biogenesis, secretion, and intercellular interactions of exosomes and other extracellular vesicles.

By Marina Colombo, G. Raposo, C. Théry. Annual Review of Cell and Developmental Biology, 2014

5,577 citations recorded by the source corpus.

Subfields: Cancer Research, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/a73f9e6e5fb92c521a7160ceab935e8986c1499c

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cancer Research

1. Raghu Kalluri
2. Marina Colombo
3. X. Breakefield
4. A. Llorente
5. C. Théry
6. M. Tkach
7. W. Stoorvogel
8. J. Kowal

In Molecular Biology

1. Raghu Kalluri
2. X. Breakefield
3. C. Théry
4. Marina Colombo
5. A. Llorente
6. M. Tkach
7. J. Kowal
8. W. Stoorvogel

Citations in the corpus

• Extracellular Vesicles: Unique Intercellular Delivery Vehicles. (2017, background): “Extracellular vesicles (EVs) are released from cells by a variety of mechanisms, depending on their mode of biogenesis [50] (Fig.”
• Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers (2020, background): “EVPs are actively released into the peripheral circulation at concentrations of >109 vesicles/mL, providing ample material for downstream analyses (Colombo et al., 2014).”
• Extracellular vesicles in cancer: cell-to-cell mediators of metastasis (2016, neutral): “In this review we summarize the metastatic role of various EVs: microvesicles, exosomes, ectosomes, oncosomes, cytoplast etc (Colombo et al., 2014; Di Vizio et al., 2012; Headley et al., 2016; Thery et al., 2009; van der Pol et al., 2012).”
• The exosome journey: from biogenesis to uptake and intracellular signalling (2021, background): “MVBs get transported to plasma membrane via cytoskeletal and microtubule network and undergo exocytosis post fusion with the cell surface whereby the ILVs get secreted as exosomes [25].”
• Biogenesis and secretion of exosomes. (2014, neutral): “This review will summarize the recent advances on the molecular machineries of exosome formation and secretion, but interested readers can refer to our more detailed review also discussing the other types of EVs [15].”
• Exosomes in cancer development, metastasis, and immunity (2019, background): “Microvesicles, sometimes called microparticles, are generated from the plasma membrane and have diameters ranging from 100 nm to 1000 nm [6].”
• Proteomic comparison defines novel markers to characterize heterogeneous populations of extracellular vesicle subtypes (2016, background): “Antibodies for Western blot were: mouse monoclonal anti-human CD63 (clone H5C6, BD Biosciences), CD9 (clone CBL162,Millipore), CD81 (clone B-11, Santa-Cruz), flotillin-1 (clone 18/Flotillin-1, BD Biosciences), MHC class II [1B5 hybridoma anti-DRa (39)], actin (clone c4, Millipore), ADAM10 (clone #16”