Four deaths and a funeral: from caspases to alternative mechanisms

By Marcel Leist, M. Jäättelä. Nature reviews. Molecular cell biology, 2001

1,737 citations recorded by the source corpus.

Subfields: Cell Biology, Epidemiology, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/35a080020864c0a835b3d948b14e2d8b4407024a

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Citations in the corpus

Nitric oxide‐induced mitochondrial fission is regulated by dynamin‐related GTPases in neurons (2006, background): “Both caspase-dependent and independent pathways appear to operate in the neuronal loss in neurodegenerative disorders (Li et al, 2000; Leist and Jaattela, 2001; Friedlander, 2003; Cregan et al, 2004).”
The heat shock protein 70 family: Highly homologous proteins with overlapping and distinct functions (2007, background): “hydrolases into the cytosol, where they can initiate apoptosis-like programmed cell death [68,73,74].”
Adipocyte death defines macrophage localization and function in adipose tissue of obese mice and humans Published, JLR Papers in Press, September 8, 2005. DOI 10.1194/jlr.M500294-JLR200 (2005, background): “bodies containing nuclear fragments (26, 27, 39).”
The role of apoptosis in creating and maintaining luminal space within normal and oncogene-expressing mammary acini. (2002, background): “In cesses, including autophagic death and paraapoptosiscontrast, vector-infected (pBABE) controls at the same (Bursch et al., 2000; Leist and Jaattela, 2001; Sperandiotime points were hollow (Figure 5D).”
Tumor necrosis factor signaling (2003, background): “independent of caspases, morphologically quite different from apoptosis and in vivo associated with inflammation.(284)”
Molecular Mechanisms of Ischemia-Reperfusion Injury in Brain: Pivotal Role of the Mitochondrial Membrane Potential in Reactive Oxygen Species Generation (2012, background): “Morphologic and biochemical analyses indicate that both necrotic and apoptotic events occur simultaneously [84, 116], and evidence linking various pathways suggests that a degree of cross talk exists that results in cell death occurring in a spectrum between apoptosis and necrosis [117].”
Apoptosis, Pyroptosis, and Necrosis: Mechanistic Description of Dead and Dying Eukaryotic Cells (2005, background): “It has also been demonstrated in a variety of systems that stimuli initiating caspase-dependent apoptosis will cause cell death, albeit by a different mechanism, even in the presence of caspase inhibitors (54, 66).”
Necrosis: a specific form of programmed cell death? (2003, background): “During the past years, a number of data emerged demonstrating wide occurrence of caspase-independent programmed cell death, both apoptotic and necrotic [141,142].”
Lysosomes and autophagy in cell death control (2005, background): “— it is possible that alternative, non-apoptotic cell death pathways are also relevant to carcinogenesi”
Autophagy as a cell death and tumor suppressor mechanism (2004, background): “However, even upon inhibition of apoptosis, cell death may still proceed due to the activation of nonapoptotic pathways (Leist and Jaattela, 2001).”
Autophagy: dual roles in life and death? (2005, background): “Several other forms of cell death have been described on the basis of studies in derived cell lines (reviewed in Ref”
Necrosis, a well-orchestrated form of cell demise: signalling cascades, important mediators and concomitant immune response. (2006, background): “Caspase-independent cell death can provide a backup suicide mechanism if the classical apoptosis machinery fails [9,10].”