Cell death by mitotic catastrophe: a molecular definition

By M. Castedo, J. Perfettini, T. Roumier, K. Andréau, R. Medema, Guido Kroemer. Oncogene, 2004

1,280 citations recorded by the source corpus.

Subfields: Cell Biology, Molecular Biology, Oncology

View Paper: https://www.semanticscholar.org/paper/357aa4ebb0ac20bd1dc3a1a835fb6d4b4e9479c4

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cell Biology

1. Guido Kroemer
2. Beth Levine
3. D. Klionsky
4. Douglas R. Green
5. L. Galluzzi
6. J. Cubillos-Ruiz
7. Junying Yuan
8. Y. Tsujimoto

In Molecular Biology

1. Guido Kroemer
2. Douglas R. Green
3. L. Galluzzi
4. Beth Levine
5. Simone Fulda
6. D. Tang
7. Junying Yuan
8. D. Klionsky

In Oncology

1. Guido Kroemer
2. L. Galluzzi
3. D. Tang
4. Douglas R. Green
5. Scott J. Dixon
6. A. Letai
7. L. Zitvogel
8. Karen H. Vousden

Citations in the corpus

• Cell Death Signaling. (2015, background): “These include mitotic catastrophe (Castedo et al. 2004), ferroptosis (Dixon et al.”
• p53-deficient cells rely on ATM- and ATR-mediated checkpoint signaling through the p38MAPK/MK2 pathway for survival after DNA damage. (2007, background): “A hallmark of mitotic catastrophe is entry of cells into mitosis despite the presence of damaged DNA, resulting in activation of the apoptotic cell death pathway (Castedo et al., 2004).”
• Diagnosing and exploiting cancer's addiction to blocks in apoptosis (2008, background): “Death following mitotic catastrophe, however, might be simply another means of entry into the apoptotic pathwa”
• Mitotic catastrophe: a mechanism for avoiding genomic instability (2011, background): “, raising the possibility that mitotic catastrophe might constitute a prelude to apoptotic or necrotic cell death rather than a bona fide cell death mechanis”
• Neuronal Cell Death. (2018, positive): ““Mitotic catastrophe” refers to cell death induced by aberrant mitosis (94, 682, 700).”
• Radiation-induced cell death mechanisms (2010, background): “Mitotic catastrophes in apoptosis-competent cells are frequently followed by a delayed type of apoptosis [72, 74, 80, 82, 84 , 88].”
• A guide to cell death pathways (2023, positive): “Biochemi-cally, mitotic catastrophe is characterized by premature condensation of under-replicated or damaged chromosomes with double-stranded DNA breaks at the centromere 200 .”
• Molecular definitions of cell death subroutines: recommendations of the Nomenclature Committee on Cell Death 2012 (2011, background): “During the past decade, several attempts have been made to delineate the molecular pathways leading to mitotic catastrophe.(5,8,105,106) Occasionally, researchers restrictively”
• Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018 (2018, background): “(two potential consequences of chromosomal missegregation) as well as micronucleation (perhaps resulting from the persistence of lagging or acentric chromosomes) [974, 975].”
• Mitochondrial membrane permeabilization in cell death. (2007, background): “Cell death occurring during the metaphase/anaphase transition is often characterized by the activation of caspase-2 (which can occur in response to DNA damage) (96) and/or MMP with release of cell death effectors such as AIF and the caspase-9 and -3 activator Cyt c (553).”