Structure-stability-function relationships of dendritic spines.

By Haruo Kasai, Masanori Matsuzaki, J. Noguchi, N. Yasumatsu, Hiroyuki Nakahara. Trends in Neurosciences, 2003

884 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Cognitive Neuroscience

View Paper: https://www.semanticscholar.org/paper/34a5dd3e7092a4ad1b249db1b05728575d93fc58

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In Cellular and Molecular Neuroscience

In Cognitive Neuroscience

Citations in the corpus

The role of the Rho GTPases in neuronal development. (2005, background): “branching and spine morphology, and since spine shape and function are intricately linked (Engert and Bonhoeffer 1999; Maletic-Savatic et al. 1999; Toni et al. 1999; Matsuzaki et al. 2001; Yuste and Bonhoeffer 2001; Kasai et al. 2003), the observed changes are likely to impair neuronal connectivity ”
Learning rules and persistence of dendritic spines (2010, background): “Structure and function correlate under physiological conditions, probably because both are regulated by actin fibers (Kim & Lisman, 1999; Krucker et al., 2000; Kasai et al., 2003) (SLR15).”
Pyramidal neurons: dendritic structure and synaptic integration (2008, background): “It has been suggested that thin, dynamic spines might be available to contribute to learning, whereas larger, more stable spines might be involved in the storage of established memorie”
Drug Addiction as a Pathology of Staged Neuroplasticity (2008, background): “In addition to alterations in spine morphology another consequence of increased actin cycling would be alterations in the trafficking of proteins into the postsynaptic membrane (Kasai et al, 2003).”
Estrogen Actions in the Brain and the Basis for Differential Action in Men and Women: A Case for Sex-Specific Medicines (2010, background): “In terms of sex hormone actions, particular attention has been given to the density of dendritic spines, mainly in the CA1 pyramidal cells, because these structures receive excitatory inputs that are key to synaptic plasticity and learning (Kandel, 2001; Kasai et al., 2003).”
Structural plasticity associated with exposure to drugs of abuse. (2004, neutral): “…and dendritic spines are thought to be a locus of experience-dependent structural plasticity (Harris and Kater, 1994; Nimchinsky et al., 2002; Kasai et al., 2003; Lamprecht and LeDoux, 2004), and therefore, they provide an obvious focus of study in trying to understand how experiences can…”
Do thin spines learn to be mushroom spines that remember? (2007, background): “These features suggest that mushroom spines are more stable ‘memory spines’ [17].”
Molecular mechanisms of dendritic spine morphogenesis. (2006, background): “Why is the morphology of spines important? There is strong correlation between the size of the spine head and the strength of the synapse, presumably related to the higher levels of AMPA receptors in larger spines (Figure 1) [9].”
Spinogenesis and Pruning Scales across Functional Hierarchies (2009, background): “Would this observation also be true for TE and PFC we might conclude that many of these spines simply did not form synapses [for review, see Kasai et al. (2003) and Bourne and Harris (2007)].”
Structural basis of long-term potentiation in single dendritic spines (2004, background): “The memory stored in large spines might thus be protected from further potentiation caused by its readout and new memory formatio”
Alleviating catastrophic forgetting using context-dependent gating and synaptic stabilization (2018, background): “Consistent with this notion, neuroscience studies have proposed that diverse mechanisms operating at the systems (Cichon and Gan, 2015; Tononi and Cirelli, 2014), morphological (Kasai et al., 2003; Yoshihara et al., 2009), and transcriptional (Kukushkin and Carew, 2017) levels all act to stabilize l”
Actin in dendritic spines: connecting dynamics to function (2010, background): “Experimental evidence has shown that changes in spine morphol ogy account for functional differences at the synaptic level (Yuste and Bonhoeffer, 2001; Kasai et al., 2003).”
Regulatory mechanisms of AMPA receptors in synaptic plasticity (2007, background): “Indeed, there is a good correlation between spine size and synaptic strengt”