Structural basis of long-term potentiation in single dendritic spines

By Masanori Matsuzaki, N. Honkura, G. Ellis‐Davies, Haruo Kasai. Nature, 2004

2,441 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Materials Chemistry

View Paper: https://www.semanticscholar.org/paper/a5a878f17363750c26079a3c5be0ae09796402c3

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Citations in the corpus

Dendritic protein synthesis, synaptic plasticity, and memory. (2006, background): “A recent study reported “synapse-specific” morphological changes (Matsuzaki et al., 2004), but close examination of the figures shown suggests that nearby synapses also change.”
Hebbian and Homeostatic Plasticity Mechanisms in Regular Spiking and Intrinsic Bursting Cells of Cortical Layer 5 (2015, neutral): “There is evidence that LTP can lead to increases in the number of spines or the input-specific gain of individual spines, both functions that add excitatory drive to the cell (Engert and Bonhoeffer, 1999; Matsuzaki et al., 2004).”
Do thin spines learn to be mushroom spines that remember? (2007, background): “Both large and small spines undergo the same absolute increase in head volume and surface area [37,38 ].”
Molecular mechanisms of dendritic spine morphogenesis. (2006, background): “LTP-inducing stimuli cause formation of new spines and enlargement of existing spines [ 10 ,13,14], whereas long-term depression (LTD)-inducing stimulation is associated with shrinkage and/or retraction of spines [13‐15 ]( Figure 1). On the one hand, LTD requires both calcineurin and protein phospha”
Soluble oligomers of amyloid β-protein facilitate hippocampal long-term depression by disrupting neuronal glutamate uptake (2009, positive): “Anatomical studies in normal rodents suggest that the induction of LTP is associated with spine formation and increased spine volume, whereas the induction of long-term synaptic depression (LTD) results in decreased spine volume and spine elimination (Matsuzaki et al., 2004; Nägerl et al., 2004; Zho”
The dendritic branch is the preferred integrative unit for protein synthesis-dependent LTP (2011, methodology): “We found, in agreement with published data (Asrican et al., 2007; Matsuzaki et al., 2004; Smith et al., 2003), that the uEPSC amplitude measured at a spine was directly proportional to its volume (Figures S3A–S3E).”
Synaptic Plasticity: Multiple Forms, Functions, and Mechanisms (2008, background): “…changes which have been reported to accompany LTP include growth of new dendritic spines, enlargement of preexisiting spines and their PSDs, and the splitting of single PSDs and spines into two functional synapses (Abraham and Williams, 2003; Matsuzaki et al, 2004; Yuste and Bonhoeffer, 2001).”
Synaptic plasticity and addiction (2007, background): “, and there is growing evidence that LTP is accompanied by observable enlargements of dendritic spines and associated postsynaptic densitie”
Mechanisms of CaMKII action in long-term potentiation (2012, background): “Nearby synapses that are only micrometres away are not potentiate”
Stress, Depression, and Neuroplasticity: A Convergence of Mechanisms (2008, background): “In recent years, growth of new dendritic spines and enlargement of existing spines have been demonstrated after LTP-inducing synaptic stimulation (Engert and Bonhoeffer, 1999; Matsuzaki et al, 2004).”
Modeling the dynamic interaction of Hebbian and homeostatic plasticity. (2014, methodology): “We assume the output activity is given by y =wx and take the input activity x to be constant in each condition, x = 1 for normal visual experience, and x 1 under MD (for simplicity we take activities and weights to be unitless numbers).”