Level of action of cathodal DC polarisation induced inhibition of the human motor cortex.

By Michael A. Nitsche, Maren S Nitsche, C. Klein, F. Tergau, John C. Rothwell, Walter Paulus. Clinical Neurophysiology, 2003

729 citations recorded by the source corpus.

Subfields: Neurology, Psychiatry and Mental health, Surgery

View Paper: https://www.semanticscholar.org/paper/31699e5d90346e21a06040820d8419cc7b7f43a7

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Citations in the corpus

Pharmacological Modulation of Cortical Excitability Shifts Induced by Transcranial Direct Current Stimulation in Humans (2003, background): “For healthy human subjects, it has already been shown that tDCS can modulate neuroplastic changes (Rosenkranz et al. 2000; Nitsche et al. 2003b).”
Transcranial direct current stimulation: State of the art 2008 (2008, background): “For tDCS durations resulting in long-lasting after-effects (1 hour or more), an intersession interval of 48 hours to 1 week has been suggested.(14,15,43) If repetitive tDCS is performed to prolong and stabilize long-lasting after-effects, subjects are generally stimulated once a day.”
Partially non‐linear stimulation intensity‐dependent effects of direct current stimulation on motor cortex excitability in humans (2013, methodology): “Accordingly, the after-effects of tDCS are caused by calcium-dependent mechanisms (Nitsche et al. 2003a).”
Therapeutic effects of non-invasive brain stimulation with direct currents (tDCS) in neuropsychiatric diseases (2014, positive): “The resulting plasticity involves glutamatergic 96 synapses, and is calcium-dependent (Nitsche et al., 2003a, 2004b; 97 Stefan et al., 2002; Wolters et al., 2003).”
How does transcranial DC stimulation of the primary motor cortex alter regional neuronal activity in the human brain? (2005, background): “Consistent with animal data, these changes in excitability persist beyond the time of stimulation if tDCS is given for more than 3 min (Nitsche & Paulus, 2000) and remain stable for at least an hour if tDCS is given for ‡ 10 min (Nitsche & Paulus, 2001; Nitsche et al., 2003a).”
Effects of transcranial direct current stimulation (tDCS) on human regional cerebral blood flow (2011, background): “…(tDCS) on human regional cerebral blood flow, NeuroImage (2011), doi:10.1016/j.neuroimage.2011.06.018 been observed in implicit motor learning (Nitsche et al., 2003a, 2003b, 2003c), sensorimotor skills (Reis et al., 2009; Vines et al., 2006a, 2006b, 2008a, 2008b), visuomotor coordination…”
A technical guide to tDCS, and related non-invasive brain stimulation tools (2015, background): “For safety aspects in a strict sense, structural damage of brain tissue can be ruled out for motor cortex stimulation protocols introduced by Nitsche and colleagues (Nitsche and Paulus, 2001; Nitsche et al., 2003).”
Shaping the effects of transcranial direct current stimulation of the human motor cortex. (2007, background): “In experiment 1, the currents flowed continuously for 4 s (excitability shifts during tDCS, experiment 1a) or 7 min (short-lasting aftereffects, experiment 1b), to cover both intra-and aftereffects of tDCS (Nitsche and Paulus 2000, 2001; Nitsche et al. 2003a).”
Transcranial DC stimulation (tDCS): a tool for double-blind sham-controlled clinical studies in brain stimulation. (2006, background): “…direct current stimulation (tDCS) influences cognitive functions in healthy volunteers (Antal et al., 2004; Fregni et al., 2005a; Iyer et al., 2005; Nitsche et al., 2003a) and transiently enhances motor performance in patients with chronic stroke (Hummel et al., 2005a; Hummel and Cohen, 2005;…”
Preconditioning of Low-Frequency Repetitive Transcranial Magnetic Stimulation with Transcranial Direct Current Stimulation: Evidence for Homeostatic Plasticity in the Human Motor Cortex (2004, background): “In accordance with previous reports (Nitsche and Paulus, 2001; Nitsche et al., 2003), anodal TDCS induced a long-lasting increase in corticospinal excitability, whereas cathodal TDCS resulted in a sustained decrease in corticospinal excitability.”
Modulation of cortical excitability by weak direct current stimulation--technical, safety and functional aspects. (2003, background): “that they do not cause heating effects under the electrode (Nitsche and Paulus, 2000), do not elevate serum neurone-specific enolase level (Nitsche and Paulus, 2001; Nitsche et al., 2003), a sensitive marker of neuronal damage (Steinhoff et al.”
Mechanisms and Controversies of tACS (Transcranial Alternating Current Stimulation) (2024, background): “Why do reported effects take time to occur (typically, at least 5 to 10 minutes is the “golden duration” used in most studies that is required to reach detectable effects, deriving from (Nitsche & Paulus, 2001) and (Nitsche et al., 2003), among others)?”