A decrease of the butyrate-producing species Roseburia hominis and Faecalibacterium prausnitzii defines dysbiosis in patients with ulcerative colitis

By K. Machiels, M. Joossens, J. Sabino, V. De Preter, I. Arijs, V. Eeckhaut, V. Ballet, K. Claes, F. Van Immerseel, K. Verbeke and 4 more. Gut, 2013

1,715 citations recorded by the source corpus.

Subfields: Genetics, Infectious Diseases, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/2e547f47592355b756bd89acb37538c161c52ba6

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Citations in the corpus

Understanding the Holobiont: How microbial metabolites affect human health and shape the immune system (2017, background): “…is associated with a decrease 4 Cell Metabolism 26, July 5, 2017 of SCFA-producing microbial species in the gut, and dietary changes that promote production of SCFAs by the microbiome can ameliorate symptoms (Frank et al., 2007; Kanauchi et al., 2002; Machiels et al., 2014; Sokol et al., 2009).”
Short chain fatty acids and its producing organisms: An overlooked therapy for IBD? (2021, background): “prausnitzii, Bifidobacterium adolescentis, Dialister invisus and other SCFA-producing microbiota has been reported [5,61].”
Microbiota metabolite short chain fatty acids, GCPR, and inflammatory bowel diseases (2016, background): “Furthermore, a recent study suggested that the dybiosis, characterized by a decrease of the butyrate-producing species Roseburia hominis and Eaecalibacterium prausnitizii, was defined in patients with UC [7].”
GENETICS AND PATHOGENESIS OF INFLAMMATORY BOWEL DISEASE (2016, background): “Interestingly, it was noted in a separate study that there is a reduction in short-chain fatty acid (predominantly propionate and acetate but not butyrate) in UC patients (93).”
Intestinal Short Chain Fatty Acids and their Link with Diet and Human Health (2016, background): “For instance, butyrate producers are normally low in ulcerative colitis (Machiels et al., 2014) and reduced levels of propionate producers have been detected in children at risk of asthma (Arrieta et al., 2015).”
Intestinal Permeability in Inflammatory Bowel Disease: Pathogenesis, Clinical Evaluation, and Therapy of Leaky Gut (2015, background): “Another potential mechanism of action is the restoration of butyrate-producing bacteria: UC patients have reduced bacterial species like Faecalibacterium prausnitzii [133, 139] and supplementation with butyrate-producing species or probiotics along with preformed butyrate showed efficacy in experime”
Alteration of Gut Microbiota in Inflammatory Bowel Disease (IBD): Cause or Consequence? IBD Treatment Targeting the Gut Microbiome (2019, neutral): “Human Roseburia hominis, Faecalibacterium prausnitzii Decrease [161]”
Impacts of Gut Bacteria on Human Health and Diseases (2015, background): “A recent study observed a reduction of Roseburia hominis and Faecalibacterium prausnitzii in fecal samples of UC patients, and both species showed an inverse correlation with disease activity [58].”
Metformin Is Associated With Higher Relative Abundance of Mucin-Degrading Akkermansia muciniphila and Several Short-Chain Fatty Acid–Producing Microbiota in the Gut (2016, background): “, inflammatory bowel disease), highlighting the role of SCFAs in disease resistance (39,40).”
Short-Chain Fatty-Acid-Producing Bacteria: Key Components of the Human Gut Microbiota (2023, background): “Studies focusing on the effects of high-fiber diets, such as Mediterranean, vegetarian, and vegan diets, on patients affected by IBD, resulted in improvements in microbiome outcomes (i cre se in alpha diversity, increase in specific microbial population, etc.), in laboratory exams (reduction in C-re”