Impacts of Gut Bacteria on Human Health and Diseases
By Yu-Jie Zhang, Sha Li, R. Gan, Tong Zhou, Dong-ping Xu, Huabin Li. International Journal of Molecular Sciences, 2015
893 citations recorded by the source corpus.
Gut bacteria are an important component of the microbiota ecosystem in the human gut, which is colonized by 1014 microbes, ten times more than the human cells. Gut bacteria play an important role in human health, such as supplying essential nutrients, synthesizing vitamin K, aiding in the digestion of cellulose, and promoting angiogenesis and enteric nerve function. However, they can also be potentially harmful due to the change of their composition when the gut ecosystem undergoes abnormal changes in the light of the use of antibiotics, illness, stress, aging, bad dietary habits, and lifestyle. Dysbiosis of the gut bacteria communities can cause many chronic diseases, such as inflammatory bowel disease, obesity, cancer, and autism. This review summarizes and discusses the roles and potential mechanisms of gut bacteria in human health and diseases.
Subfields: Gastroenterology, Molecular Biology, Physiology
View Paper: https://www.semanticscholar.org/paper/5c11d4fbd5c1e48e38ce5fecb8f50b45d99a054c
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Citations in the corpus
- Colorectal Carcinoma: A General Overview and Future Perspectives in Colorectal Cancer (2017, background): “For instance, the condition known as dysbiosis, in which the natural relationship between the host and the intestinal microbiota is disrupted [137–140], is considered to be one of the most probable causes of inflammatory bowel disease (IBD) [141–144] or colorectal cancer (CRC) [142,144–147].”