BAFF AND APRIL: a tutorial on B cell survival.

By F. Mackay, P. Schneider, P. Rennert, J. Browning. Annual Review of Immunology, 2003

1,054 citations recorded by the source corpus.

Subfields: Cancer Research, Immunology

View Paper: https://www.semanticscholar.org/paper/2be6f0ca1afb800946b18d4d46ba1f52680d9f40

How researchers see this paper

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In Cancer Research

1. S. Ghosh
2. M. Hayden
3. Rafi Ahmed
4. Bali Pulendran
5. A. West
6. N. Perkins
7. M. Karin
8. Shao-Cong Sun

In Immunology

1. Bali Pulendran
2. S. Ghosh
3. Rafi Ahmed
4. M. Hayden
5. A. West
6. F. Mackay
7. Carola G. Vinuesa
8. R. Noelle

Citations in the corpus

• Cellular and genetic mechanisms of self tolerance and autoimmunity (2005, background): “Extrinsic regulation of self-reactive receptors by limiting immunogenic costimuli: (11) Controls on availability of extrafollicular T-cell help; (12) Control of TLR ligands and signalling; (13) B-cell death induced by FASL from T cells; (14) BCR inhibition of plasma-cell differentiation; (15) Contro”
• Importance of Cellular Microenvironment and Circulatory Dynamics in B Cell Immunotherapy1 (2005, background): “As an example of such survival factors, we analyzed the contribution of the B cell-activating factor belonging to the TNF family (BAFF)/BLyS/TALL-1 member of the TNF superfamily (17).”
• BCMA Is Essential for the Survival of Long-lived Bone Marrow Plasma Cells (2004, background): “Previous papers have demonstrated the ability of TACI-Ig to block BLyS ligand–receptor interactions (6, 19).”
• Mutations in TNFRSF13B encoding TACI are associated with common variable immunodeficiency in humans (2005, background): “BAFF (B cell–activating factor, also called BLyS, THANK, TALL-1 and zTNF4; encoded by TNFSF13B ) binds three TNF-like receptors selectively expressed on B cells called BAFFR (BAFF receptor, encoded by TNFRSF13C ), TACI (transmembrane activator and CAML interactor, encoded by TNFRSF13B ) and BCMA ”
• Translating innate immunity into immunological memory: implications for vaccine development. (2006, positive): “Recently, it has been demonstrated that the TNF family member BAFF/ BlyS promotes the survival of naive B cells in the periphery (Mackay et al., 2003) as well as marginal-zone B cells (Lopez-Cavalho and Kearney, 2004).”
• Cracking the BAFF code (2009, background): “Expression of BAFF, APRIL and their receptors BAFF and APRIL are mainly produced by innate immune cells such as neutrophils, macrophages, monocytes, dendritic cells (DCs) and follicular DCs (FDCs) (reviewed in Ref”
• NF-κB and the immune response (2006, background): “However, rather than acting downstream of tonic BCR signaling, recent studies have implicated signaling from BAFFR in this aspect of the B lymphocyte survival (reviewed in Mackay et al., 2003).”
• TACI and BAFF-R mediate isotype switching in B cells (2005, background): “The fact that BCMA fails to activate CSR may be due to the fact that the majority of BCMA has a low surface density and most of it is intracellular (6).”