Biofilm Dispersal: Mechanisms, Clinical Implications, and Potential Therapeutic Uses

By J. Kaplan. Journal of dentistry research, 2010

868 citations recorded by the source corpus.

Subfields: Endocrinology, Molecular Biology, Periodontics

View Paper: https://www.semanticscholar.org/paper/24852e16958d3d7b120b6c3c1c83a5e8243bc95c

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Citations in the corpus

Healthcare-associated infections, medical devices and biofilms: risk, tolerance and control. (2015, background): “The presence of other micro-organisms within the biofilm can influence dispersal through chemical signals such as acylhomoserine lactones, diffusible fatty acids and peptides (Hall-Stoodley et al., 2004; Kaplan, 2010).”
Bacterial Biofilms: Development, Dispersal, and Therapeutic Strategies in the Dawn of the Postantibiotic Era (2013, background): “Dispersin-B treatment has been shown to be effective against S. aureus and S. epidermidis biofilms and other PNAG-containing bacteria (Izano et al. 2008; Kaplan 2010).”
Biofilm Formation in Food Processing Environments is Still Poorly Understood and Controlled (2014, background): “To date three distinct modes of biofilm dispersal have been identified: (1) erosion, the continuous release of single cells or small clusters of cells from a biofilm at low levels over the course of biofilm formation, (2) sloughing, the sudden detachment of large portions of the biofilm, usually dur”
A review of microbial biofilms of produce: Future challenge to food safety (2012, background): “Dispersal: Biofilms forming microorganisms may detach due to various reasons, such as presence of QS molecules, nutrient accessibility, surface character changes, as well as physical forces from the produce (67).”
Surviving as a community: antibiotic tolerance and persistence in bacterial biofilms (2019, background): “In both cases, when Dispersin B is combined with antibiotics, the compound shows efficacy in prevention of bacterial infections (Kaplan, 2010).”
Horizontal Gene Exchange in Environmental Microbiota (2011, background): “This increased attention to the clinical aspects of biofilm communities was primarily dictated by their role in human disease (Parsek and Singh, 2003; Fux et al., 2005; Lindsay and von Holy, 2006; Estrela et al., 2009; Kaplan, 2010).”
Pseudomonas aeruginosa: new insights into pathogenesis and host defenses. (2013, background): “Continued maturation of the biofilm leads to mushroom-shaped structures that are interspersed with fluid-filled channels allowing for the exchange of waste products and nutrients (Kaplan, 2010).”
Understanding bacterial biofilms: From definition to treatment strategies (2023, background): “Low expression levels of c-di-GMP can inhibit the formation of bacterial biofilms and promote biofilm separation (Kaplan, 2010).”
Biofilms in the Food Industry: Health Aspects and Control Methods (2018, background): “Some options for this removal are glycoside hydrolases (such as Dispersin B, produced by Aggregatibacter actinomycetemcomitans) and proteases (such as proteinase K, a serine protease from the fungus Engyodontium album) (Kaplan, 2010; Fagerlund et al., 2016).”
Should we stay or should we go: mechanisms and ecological consequences for biofilm dispersal (2011, background): “In addition, there are several bacterially derived signals that induce dispersal (reviewed in Ref”
Staphylococcus aureus biofilms: recent developments in biofilm dispersal (2014, background): “…has been the focus of many recent studies due to its importance in chronic infections and the biofilm model of growth, and an analysis of major dispersal mechanisms has led to the development of dispersal-mediated treatment options for biofilm infections (Kaplan, 2010; Boles and Horswill, 2011).”
Beyond Risk: Bacterial Biofilms and Their Regulating Approaches (2020, background): “…themselves in response to changes in their environment such as antimicrobial stress, matrix-degrading enzymes and nutrient starvation, or passive behaviors (i.e., sloughing and erosion) mediated by external forces such as shear forces (Kaplan, 2010; Fleming and Rumbaugh, 2017; Lee and Yoon, 2017).”