Identification of tissue-specific microRNAs from mouse.

By M. Lagos‐Quintana, R. Rauhut, A. Yalçin, Jutta Meyer, Winfried Lendeckel, Thomas Tuschl. Current Biology, 2002

3,380 citations recorded by the source corpus.

Subfields: Cancer Research, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/1fd47f186f4c40b32a98b8f90040b06d9ddad7aa

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cancer Research

1. David P. Bartel
2. Carlo Maria Croce
3. Phillip D. Zamore
4. V. Narry Kim
5. Scott M. Hammond
6. Nikolaus Rajewsky
7. Frank J. Slack
8. Phillip A. Sharp

In Molecular Biology

1. David P. Bartel
2. Phillip D. Zamore
3. Carlo Maria Croce
4. V. Narry Kim
5. Scott M. Hammond
6. Thomas Tuschl
7. Phillip A. Sharp
8. Nikolaus Rajewsky

Citations in the corpus

• Development of microRNA therapeutics is coming of age (2014, neutral): “…from zebrafish to man and implicated in the regulation of hepatic cholesterol, lipid and iron metabolism and in maintaining liver cell identity (Lagos-Quintana et al , 2002; Kru¨tzfeldt et al , 2005; Wienholds et al , 2005; Esau et al , 2006; Elme´n et al , 2008a,b; Castoldi et al , 2011;…”
• Human microRNAs are processed from capped, polyadenylated transcripts that can also function as mRNAs. (2004, background): “However, as a number of these intronic miRNAs are found in the antisense orientation, relative to the surrounding gene (Lagos-Quintana et al. 2003), this localization does not prove that miRNAs can be derived from pre-mRNAs.”
• The MicroRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing. (2007, background): “One of the most conserved and abundantly expressed NS-specific miRNAs is miR-124 (Lagos-Quintana et al., 2002).”
• Microarray profiling of microRNAs reveals frequent coexpression with neighboring miRNAs and host genes. (2005, background): “…brain (miR-124a, miR-9) (Lagos-Quintana et al. 2002), liver (miR-122a) (Lagos-Quintana et al. 2002), muscle (miR-1b, miR-133) (Lee and Ambros 2001; Lagos-Quintana et al. 2002; Sempere et al. 2004), and bone marrow (miR-223) (Chen et al. 2004) are often cited as having highly specific expression…”
• Human embryonic stem cells express a unique set of microRNAs. (2004, background): “The expression of miRNAs is often regulated in tissuespecific and developmental stage-specific manners (Aravin et al., 2003; Krichevsky et al., 2003; Lagos-Quintana et al., 2002; Pasquinelli et al., 2000; Sempere et al., 2003), although the regulatory mechanism is still largely unknown.”
• Novel and Mechanical Stress–Responsive MicroRNAs in Populus trichocarpa That Are Absent from Arabidopsisw⃞ (2005, methodology): “RNAs were end modified and ligated with adaptors for unidirectional polarity, RT-PCR amplified, concatamerized, and cloned into a library as described by Lau et al. (2001), Lagos-Quintana et al. (2002), and Elbashir et al. (2001).”
• Genomic profiling of microRNA and mRNA reveals deregulated microRNA expression in prostate cancer (2008, background): “The miR-1-133a cluster has been shown to regulate cell differentiation (33).”