Role of NRF2 in protection against hyperoxic lung injury in mice.

By Hye-Youn Cho, A. Jedlicka, S. Reddy, T. Kensler, Masayuki Yamamoto, Liu-yi Zhang, S. Kleeberger. American Journal of Respiratory Cell and Molecular Biology, 2002

697 citations recorded by the source corpus.

Subfields: Molecular Biology

View Paper: https://www.semanticscholar.org/paper/1c9d8ef1fd14ec69065d0c74bba520167cb955d1

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Citations in the corpus

Keap1 Is a Redox-Regulated Substrate Adaptor Protein for a Cul3-Dependent Ubiquitin Ligase Complex (2004, neutral): “3 g, lanes 2 to 5), and Cul3(1-380) (from 0.”
Molecular Mechanisms Activating the Nrf2-Keap1 Pathway of Antioxidant Gene Regulation (2005, neutral): “Elimination of Nrf2 also enhances the sensitivity of neurons and astrocytes to oxidative stress by reducing both constitutive and inducible gene expression of cytoprotective genes (58, 59).”
The role of oxidative stress in ambient particulate matter-induced lung diseases and its implications in the toxicity of engineered nanoparticles. (2008, background): “Examples of phase 2 enzymes include heme oxygenase 1 (HO-1), glutathione-S-transferase (GST) isoenzymes, NADPH quinone oxidoreductase [18], catalase, superoxide dismutase (SOD), and glutathione peroxidase (GPx) [17,19].”
The emerging role of the Nrf2–Keap1 signaling pathway in cancer (2013, background): “Mice with this SNP have reduced expression of Nrf2 and are more susceptible to hyperoxiainduced lung damage (Cho et al. 2002).”
Enhanced Expression of the Transcription Factor Nrf2 by Cancer Chemopreventive Agents: Role of Antioxidant Response Element-Like Sequences in the nrf2 Promoter (2002, background): “Moreover, these knockout mice were considerably more sensitive to the toxicities of acetaminophen, butylated hydroxytoluene, and hyperoxia (4, 6, 11) and the carcinogenicity of benzopyrene (34).”
Mechanistic Studies of the Nrf2-Keap1 Signaling Pathway (2006, background): “injury, inflammation, emphysema, asthma, lupus-like autoimmune nephritis, and macular degeneration (Aoki et al., 2001; Yoh et al., 2001; Braun et al., 2002; Cho et al., 2002; Cho et al., 2004; Gao and Talalay, 2004; Suh et al., 2004; Ishii et al., 2005; Rangasamy et al., 2005; Shih et al., 2005a; Sh”