Signal Transduction Cascades Regulating Fungal Development and Virulence

By K. Lengeler, Robert C. Davidson, Cletus D'souza, T. Harashima, W. Shen, Ping-ping Wang, Xuewen Pan, Michael S. Waugh, J. Heitman. Microbiology and Molecular Biology Reviews, 2000

967 citations recorded by the source corpus.

Subfields: Epidemiology, Infectious Diseases, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/1b34f45f8f1ceb5d83a7030208a448b9fa5adf8d

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Infectious Diseases

K. Verstrepen

In Molecular Biology

Citations in the corpus

Yarrowia lipolytica: an industrial workhorse (2010, background): “Evidence exists that external signals influencing fungal dimorphic response are basically sensed through the operation of two signaling transduction mechanism: the mitogen activated protein kinase (MAPK), and the cyclic-AMP (cAMP) dependent protein kinase (PKA) pathways [52,53,54].”
Biosynthesis of fungal melanins and their importance for human pathogenic fungi. (2003, background): “However, downstream effects of the signaling pathways differ significantly between fungal species (Lengeler et al., 2000).”
Fruiting-Body Development in Ascomycetes (2006, background): “In filamentous ascomycetes, cAMP signaling is involved in such diverse cellular processes as stress response, metabolism, pathogenicity, and sexual development (Kronstad et al. 1998; Lengeler et al. 2000).”
Flocculation, adhesion and biofilm formation in yeasts (2006, background): “Indeed, recent studies indicate that at least in Candida spp., many ALS genes are regulated by orthologues of the pathways known to regulate adhesion in S. cerevisiae (Lengeler et al., 2000; Liu, 2001; Kaur et al., 2005; Maidan et al., 2005).”
Heading for disaster: Fusarium graminearum on cereal crops. (2004, background): “MAP kinases belong to a family of serine/threonine protein kinases which activate transcription factors that function in the regulation of mating, conidiation and conidia germination, appressorium and penetration peg formation, invasive hyphal growth and response to hyperosmotic stress and cell turg”
The genome sequence of the filamentous fungus Neurospora crassa (2003, background): “In Candida albicans , capable of pseudohyphal, true hyphal and budding growth, both pathways are required for true hyphal production, suggesting a similar role in Neurospora”