Biosynthesis of fungal melanins and their importance for human pathogenic fungi.

By K. Langfelder, M. Streibel, B. Jahn, G. Haase, Axel A. Brakhage. Fungal Genetics and Biology, 2003

616 citations recorded by the source corpus.

Subfields: Cell Biology, Epidemiology, Infectious Diseases

View Paper: https://www.semanticscholar.org/paper/92ab99c2de9dcdc09fdb368558b35e80a916fca7

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cell Biology

1. J. Bok
2. N. Keller

In Epidemiology

1. N. Gow
2. K. Sterflinger

In Infectious Diseases

1. C. Munro
2. N. Gow

Citations in the corpus

• Black Yeasts and Meristematic Fungi: Ecology, Diversity and Identification (2006, background): “osmotic stress, from reactive nitrogen species, from reactive oxygen, shelter them against phagocytosis in host tissue and inhibit tumor-necrosis factors (Langfelder et al. 2003).”
• Fruiting-Body Development in Ascomycetes (2006, background): “Two biochemical pathways have been recognized for fungal melanin production, the DHN (dihydroxynaphtalene)- and the DOPA (dihydroxyphenylalanine)-melanin biosynthesis pathways (Langfelder et al. 2003).”
• Pathogenesis of Aspergillus fumigatus in Invasive Aspergillosis (2009, background): “The deletion of Afyap1, a regulator of oxidative stress response genes, or the deletion of the putative AfYap1 binding partner AfSkn7 resulted in an increased susceptibility of these mutants to H2O2 but did not alter their virulence in a neutropenic model of IA (72, 76, 106).”
• Synthesis and assembly of fungal melanin (2011, neutral): “Tautomerization of dopachrome forms dihydroxyindoles that polymerize into melanin (Land et al. 2004; Langfelder et al. 2003; Riley 1997).”
• The Fungal Cell Wall: Structure, Biosynthesis, and Function (2017, background): “In addition, DOPA-melanins can be formed by Aspergillus and other black fungi (77, 78).”
• Production of Melanin Pigment by Fungi and Its Biotechnological Applications (2017, background): “In a recent study, our group characterized the pigment produced by A. nidulans mutants as DOPA-melanin according to the results obtained with specific inhibitors of DHN- and DOPA-melanin pathways [93].”
• Fungal laccases as green catalysts for dye synthesis (2012, background): “In literature, there is a lot of information that products of the oxidative action of different laccases in the natural environment are colourful [9–13].”
• Phenolic Compounds: Introduction 50 (2013, background): “The allomelanin of the fungi Aspergillus niger, Ustilago maydis, and Daldinia appears to contain perylene (XXI) units derived from 1,8-dihydroxynaphthalene (XXII) [94–99].”
• LaeA, a Regulator of Secondary Metabolism in Aspergillus spp (2004, background): “Presumably this is due to a loss of toxin secondary metabolites or melanins, known virulence factors in several fungal systems (5, 22).”