The biology of chemokines and their receptors.

By D. Rossi, A. Zlotnik. Annual Review of Immunology, 2000

2,691 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/1a40da55ee96b8d1016ed9a2e18b4522cc875266

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Citations in the corpus

An Alternatively Spliced Variant of CXCR3 Mediates the Inhibition of Endothelial Cell Growth Induced by IP-10, Mig, and I-TAC, and Acts as Functional Receptor for Platelet Factor 4 (2003, background): “The chemokines CXCL9, CXCL10, and CXCL11 exhibit several activities, including the induction of proliferation of HMC (22, 23) and the inhibition of endothelial cell growth (4–10).”
Mediators of Chronic Obstructive Pulmonary Disease (2004, background): “Over 50 different chemokines are now recognized, and they activate up to 20 different surface receptors (Rossi and Zlotnik, 2000).”
The role of interleukin-8 and its receptors in gliomagenesis and tumoral angiogenesis. (2005, background): “Among the fi rst chemokines discovered, IL-8 was identifi ed as a chemotactic factor secreted by activated monocytes and macrophages that promotes the directional migration of neutrophils, basophils, and T lymphocytes (Baggiolini et al., 1989; Rossi and Zlotnik, 2000).”
CXCR4-activated astrocyte glutamate release via TNFα: amplification by microglia triggers neurotoxicity (2001, background): “Chemokines, a class of small proteins acting via cell-surface G protein-coupled receptors, were first identified as inflammatory mediators of leukocyte chemotaxis and have been subsequently shown to possess a much larger repertoire (for review, see ref”
Regulation of CXCR4 signaling. (2007, background): “While CXCR4 was initially cloned from leukocytes [24,25], it has since been shown to be expressed in a number of tissues in addition to cells of hematopoetic lineages [26].”
Interconversion between two unrelated protein folds in the lymphotactin native state (2008, background): “Chemokines are small, secreted proteins that induce chemotaxis by adhering to cell-surface glycosaminoglycans on vascular endothelium and stimulating specific G protein-coupled receptors (GPCRs) expressed on target leukocytes (6).”
Cancer and the chemokine network (2004, background): “gif" NDATA ITEM> ]> CHEMOKINES are chemotactic cytokines that cause the directed migration of leukocytes, and are induced by inflammatory cytokines, growth factors and pathogenic stimul”
Inflammatory and immune pathways in the pathogenesis of periodontal disease (2014, background): “In addition to their cell-trafficking role, chemokines provide messages leading to other biological processes, such as angiogenesis, cell proliferation, apoptosis, tumor metastasis and host defense (48, 171, 200, 201, 267).”
Post-translational modifications in the context of therapeutic proteins (2006, positive): “Many chemokine receptors have been shown to be tyrosine sulfated, which could render this PTM relevant to the effective functioning of processes, such as immunity, hematopoesis, angiogenesis and tumor biolog”
Microglia as a source and target of cytokines (2002, background): “An increasing body of evidence relates to the ever growing family of chemokines (Asensio and Campbell, 1999; Mennicken et al., 1999; Rossi and Zlotnik, 2000).”
Inflammation and cancer (2002, neutral): “A family of chemotactic cytokines, named chemokines, which possess a relatively high degree of specificity for chemoattraction of specific leukocyte population”
Pathological and protective roles of glia in chronic pain (2009, background): “Chemokines were initially recognized as having a role in the maturation and trafficking of leukocytes during inflammatory disease”