Cancer and the chemokine network

By F. Balkwill. Nature Reviews. Cancer, 2004

2,397 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/21ad78b42aaf8d27cfc3978885542b93e6a2cb58

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Citations in the corpus

Cytokines and their relationship to the symptoms and outcome of cancer (2008, background): “The tumour microenvironment is rich in cytokines and other inflammatory mediators that influence immunosuppression, growth of cancer cells, tissue remodelling and angiogenesi”
The role of CXC chemokines and their receptors in cancer. (2008, background): “[15] F.”
Galectins as modulators of tumour progression (2005, background): “Whereas some inflammatory cytokines and chemokines create an appropriate setting to suppress tumour growth and kill cancer cells, others have a positive impact on tumour progression and surviva”
A CXCL1 paracrine network links cancer chemoresistance and metastasis (2012, positive): “CXCL1 and 2 are 90% identical by amino acid sequence and signal through the same receptor CXCR2 (Balkwill, 2004).”
Therapeutic targeting of the tumor microenvironment. (2005, positive): “Additional proinflammatory factors that are potential targets for cancer prevention and treatment include IκB kinase (IKK), the upstream kinase that activates NF-κB (Karin et al., 2004; Lam et al., 2005), TNF-α (Palladino et al., 2003), interleukins IL-1, IL 6, and IL-8, and certain chemokines and ”
Clodronate-liposome-mediated depletion of tumour-associated macrophages: a new and highly effective antiangiogenic therapy approach (2006, background): “Chemokines and chemokine receptors have been used as targets for the development of therapeutic strategies to control inflammatory disorders, and recent results suggest that chemokine inhibitors also affect tumour growth by reducing macrophage infiltration (Balkwill, 2004).”
The role of interleukin-8 and its receptors in gliomagenesis and tumoral angiogenesis. (2005, background): “Their genes, IL-8RA and IL-8RB, each of which is encoded by a single exon, are located 20 kb apart on chromosome 2q35, and they are associated with an inactive CXCR2 pseudogene, IL-8RP (Ahuja et al., 1992, 1994).”
Bone Metastases: An Overview (2017, background): “We also know that chemokines (chemoattractive cytokines), integrins, osteopontin, bone sialoprotein and type I collagen are critical for organ colonization by cancer cells [18,19].”