Mammalian circadian biology: elucidating genome-wide levels of temporal organization.

By Phillip L. Lowrey, J. Takahashi. Annual review of genomics and human genetics (Print), 2004

1,005 citations recorded by the source corpus.

Subfields: Endocrine and Autonomic Systems

View Paper: https://www.semanticscholar.org/paper/1593bf7bdfc28281b1fab7c6542614ea546e9d12

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In Endocrine and Autonomic Systems

Citations in the corpus

Timing of food intake predicts weight loss effectiveness (2013, background): “Recent studies link energy regulation to the circadian clock at the behavioral, physiological and molecular levels,6–9 emphasizing that the timing of food intake itself may have a significant role in weight regulation.10 In this regards, there is emerging literature in animals demonstrating a relati”
CENTRAL AND PERIPHERAL CIRCADIAN CLOCKS IN MAMMALS (2012, background): “In mammals, the mechanism of the circadian clock is cell autonomous and arises from an autoregulatory negative-feedback transcriptional network (Lowrey & Takahashi 2004, Takahashi et al. 2008) (Figure 1).”
Circadian regulator CLOCK is a histone acetyltransferase. (2006, positive): “This negative-feedback regulation also drives gene expression cycles of a variety of circadian output genes (Lowrey and Takahashi, 2004).”
Suprachiasmatic Nucleus: Cell Autonomy and Network Properties (2010, background): “To serve this purpose, mammalian cells contain “circadian clocks” composed of genes that interact in oscillatory transcriptional networks within cells (1, 2) and regulate the expression of many other genes critical for cell physiology and metabolism.”
Post-translational modifications regulate the ticking of the circadian clock (2007, neutral): “Most importantly, these signals set the peripheral clocks present throughout the body (see Ref”
The curse of physiology—challenges and opportunities in the interpretation of geochemical data from mollusk shells (2008, background): “Circadian oscillators are encoded by genes (e.g., Lowrey and Takahashi 2004 ).”
Early aging and age-related pathologies in mice deficient in BMAL1, the core componentof the circadian clock. (2006, background): “Mice with mutations or targeted disruptions of core circadian genes that have been generated during the last decade all show impaired circadian behavior and deregulation of circadian patterns in gene expression (Lowrey and Takahashi 2004).”
Major depressive disorder. (2008, neutral): “Circadian rhythm is a roughly 24-hour cycle of biochemical, physiological, and behavioral processes under control of internal clock [100-102].”
Molecular Architecture of the Mammalian Circadian Clock (2013, background): “Circadian (Latin ‘circa diem’, meaning ‘about a day’) synchronization allows anticipation of regular environmental changes to influence molecular and behavioral decisions that impact fitness and survival, including food intake and metabolism, predator/prey interactions, and the evasion of DNA damage”
The Genetics of Mammalian Circadian Order and Disorder: Implications for Physiology and Disease (2008, background): “jpg" NDATA ITEM> ]> Circadian rhythms control a variety of biological processes in living systems, ranging from bacteria to human”