Porosity of 3D biomaterial scaffolds and osteogenesis.

By V. Karageorgiou, David Kaplan. Biomaterials, 2005

6,382 citations recorded by the source corpus.

Subfields: Biomedical Engineering, Oral Surgery, Surgery

View Paper: https://www.semanticscholar.org/paper/14aa4f68144b6dd48e320afd7146ec77ca95a5ee

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Citations in the corpus

Scaffolds and cells for tissue regeneration: different scaffold pore sizes—different cell effects (2016, background): “Moreover, the pore size around 100 lm favored hypoxic conditions inducing osteochondral formation before osteogenesis, whereas larger pore size ([300 lm) directly initiated osteogenesis (Karageorgiou and Kaplan 2005).”
Three-Dimensional Cell Culture Matrices: State of the Art (2008, background): “For example, scaffolds with pores larger than 500mm induced undesired fibroblastic tissue formation by osteoblasts rather than bone tissue development.(169) Pore interconnectivity is essential for proper cell migration.”
Electrophoretic deposition of biomaterials (2010, neutral): “They showed that the pores were interconnected and that pore size was between several micrometres and hundreds of micrometres, as desired for tissue engineering applications (Karageorgiou & Kaplan 2005).”
Three-Dimensional Scaffolds for Tissue Engineering Applications: Role of Porosity and Pore Size (2013, neutral): “11 The mercury is forced into the pores of the scaffolds under high pressures.”
Understanding the effect of mean pore size on cell activity in collagen-glycosaminoglycan scaffolds (2010, methodology): “Therefore maintaining a balance between the optimal pore size for cell migration and specific surface area for cell attachment is essential.(4,7) In our laboratory we use a composite scaffold fabricated from collagen and a glycosaminoglycan (GAG) for bone tissue engineering applications produced by ”
Natural origin biodegradable systems in tissue engineering and regenerative medicine: present status and some moving trends (2007, background): “Furthermore, the necessary diffusion of nutrients and metabolites in a three-dimensional environment demands highly porous scaffolds (Karageorgiou & Kaplan 2005).”
The effect of mean pore size on cell attachment, proliferation and migration in collagen-glycosaminoglycan scaffolds for bone tissue engineering. (2010, background): “However, it is important to identify the upper limits in pore size as large pores may compromise the mechanical properties of the scaffolds by increasing void volume [8].”