A functional magnetic resonance imaging study of amygdala and medial prefrontal cortex responses to overtly presented fearful faces in posttraumatic stress disorder.

By Lisa M. Shin, Christopher I. Wright, Paul A. Cannistraro, Michelle Wedig, Katherine McMullin, B. Martis, M. L. Macklin, N. Lasko, Sarah R. Cavanagh, Terri S. Krangel and 4 more. Archives of General Psychiatry, 2005

961 citations recorded by the source corpus.

Subfields: Clinical Psychology, Cognitive Neuroscience, Experimental and Cognitive Psychology

View Paper: https://www.semanticscholar.org/paper/149ecaaf2636ae8b07869cb6ad26aeec55823928

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Citations in the corpus

How Does Mindfulness Meditation Work? Proposing Mechanisms of Action From a Conceptual and Neural Perspective (2011, neutral): “…2007; social phobia, Phan, Fitzgerald, Nathan, & Tancer, 2006; obsessive-compulsive disorder, Breiter & Rauch, 1996; posttraumatic stress disorder, Shin et al., 2005; impulsive aggression, Coccaro, McCloskey, Fitzgerald, & Phan, 2007; addiction, Bechara, 2005; generalized anxiety, Monk et al.,…”
Repeated stress induces dendritic spine loss in the rat medial prefrontal cortex. (2006, background): “One potential neuroantomical substrate relevant to PTSD is the medial PFC-amygdala circuit (Newport and Nemeroff, 2000).”
Prefrontal involvement in the regulation of emotion: convergence of rat and human studies. (2006, background): “Many researchers hypothesize that the orbitofrontal or inferior frontal cortex region executes inhibitory control over the amygdala [3,7,12].”
The Temporal Dynamics Model of Emotional Memory Processing: A Synthesis on the Neurobiological Basis of Stress-Induced Amnesia, Flashbulb and Traumatic Memories, and the Yerkes-Dodson Law (2007, background): “…and the amygdala (Williams et al. [405]), which could form the basis of certain symptoms of PTSD, such as chronic hypervigilance, attention deﬁcits, and impaired executive functioning (Vermetten and Bremner [406]; Shin et al. [407]; Britton et al. [408]; Shin et al. [409]; Williams et al. [405]).”
The Neurocircuitry of Fear, Stress, and Anxiety Disorders (2011, background): “…et al, 2007), trauma-related photographs or words (Driessen et al, 2004; Hendler et al, 2003; Morey et al, 2009; Protopopescu et al, 2005), fear conditioning (Bremner et al, 2005), and fearful facial expressions (Bryant et al, 2008b; Rauch et al, 2000; Shin et al, 2005; Williams et al, 2006).”
Finally, faces find favor (2006, neutral): “, 2005; Schultz, 2005), PTSD (Shin et al., 2005); schizophrenia (Holt et al.”
Increased amygdala and insula activation during emotion processing in anxiety-prone subjects. (2007, methodology): “In light of recent observations that medial prefrontal cortex activity may be reduced in patients with posttraumatic stress disorder (PTSD) in concert with amygdala hyperreactivity, perhaps reflecting inadequate top-down regulation of the amygdala by the medial prefrontal cortex in patients with anx”
The experience of emotion. (2007, background): “…disorder (e.g., Nakao et al. 2005, Valente et al. 2005), posttraumatic stress disorder (e.g., Bryant et al. 2005; Rauch et al. 2000; Shin et al. 2004, 2005), social anxiety and generalized anxiety disorder (for a review see Stein et al. 2002), and panic disorder (e.g., Kent et al.…”
Fear extinction in rats: implications for human brain imaging and anxiety disorders. (2006, background): “Shin et al. (2005). we predict that vmPFC activity during extinction recall would be diminished in patients with anxiety disorders such as PTSD.”
Functional neuroimaging of anxiety: a meta-analysis of emotional processing in PTSD, social anxiety disorder, and specific phobia. (2007, background): “(2005) (7) 13 13 Fearful and happy faces Fearful-happy No fMRI”
The diagnosis of mental disorders: the problem of reification. (2010, positive): “F or p er so na l u se o nl y. activation (Etkin & Wager 2007; Nitschke et al. 2009; Shin et al. 2004, 2005; Yehuda & LeDoux 2007).”
Reduced resting-state functional connectivity between amygdala and orbitofrontal cortex in social anxiety disorder (2011, background): “…associated with orbitofrontal reactivity during the suppression of negative emotions (Phan et al., 2005) and presence of threatening stimuli (Garcia et al., 1999), in generalized anxiety disorder (Monk et al., 2008) and posttraumatic stress disorder (Shin et al., 2005; Williams et al., 2006).”
Neurocircuitry models of posttraumatic stress disorder and extinction: human neuroimaging research--past, present, and future. (2006, background): “Shin et al (2005) reported similar findings in an fMRI study involving the presentation of fearful versus happy facial expressions in an independent sample of individuals with PTSD.”
Regulation of the Hypothalamic‐Pituitary‐Adrenocortical Stress Response (2016, neutral): “Human imaging studies link the subgenual anterior cingulate cortex (sgACC, area 25) with both depression and PTSD (41,110,148).”