Selective Suppression of Endothelial Cell Apoptosis by the High Molecular Weight Form of Adiponectin
By Hideki Kobayashi, N. Ouchi, S. Kihara, K. Walsh, M. Kumada, Y. Abe, T. Funahashi, Yuji Matsuzawa. Circulation Research, 2004
671 citations recorded by the source corpus.
Subfields: Literature and Literary Theory, Management, Monitoring, Policy and Law
View Paper: https://www.semanticscholar.org/paper/06787bab194cecfecc47aaab0ef4ec29fb98f8f9
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In Literature and Literary Theory
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Citations in the corpus
- Regulation of abdominal adiposity by probiotics (Lactobacillus gasseri SBT2055) in adults with obese tendencies in a randomized controlled trial (2010, background): “…multimer is more responsible than the LMW and MMW multimers for the favorable activities of adiponectin, including its insulin-sensitizing effects (Kobayashi et al., 2004; Hara et al., 2006; Nakashima et al., 2006); these findings suggest the importance of considering multimer distribution as…”
- Adiponectin-mediated modulation of hypertrophic signals in the heart (2004, background): “In contrast, the HMW form of adiponectin appears to be specific for its vascular-protective action”
- Adipose tissue dysfunction in obesity, diabetes, and vascular diseases. (2008, background): “Indeed, HMW-adiponectin levels were selectively suppressed in obese patients with ischaemic heart disease and were restored after weight loss.(101)”
- Adipose tissue as an endocrine organ. (2010, background): “For instance, the decreased serum levels of total adiponectin associated with type 2 diabetes is almost exclusively due to a decrease in levels of the circulating HMW isoform, without an accompanying reduction in levels of the other two oligomeric forms (Kobayashi et al., 2004).”
- Adiponectin and adiponectin receptors. (2005, background): “More recently, selective suppression of endothelial cell apoptosis via AMPK activation by the HMW form of adiponectin has been reported (65).”
- Adiponectin, Leptin, and Fatty Acids in the Maintenance of Metabolic Homeostasis Through Adipose Tissue Crosstalk (2016, background): “This depression in adipose glucose clearance is a result of adipose tissue hypoxia, fibrosis, and the resultant inflammatory, lipotoxic response (Kim et al., 2007; Kusminski et al., 2012).”
- Adiponectin, a Therapeutic Target for Obesity, Diabetes, and Endothelial Dysfunction (2017, background): “Mechanistically, many of the adiponectin benefits connected to its vasculoprotective are carried out via its ability to increases nitric oxide production through the activation of eNOS by AMPK-dependent manner [74,75].”
- Adiponectin protects against myocardial ischemia-reperfusion injury through AMPK- and COX-2–dependent mechanisms (2005, background): “Adiponectin stimulation inhibits apoptosis of endothelial cells through an AMPK-dependent mechanis”
- Mechanisms linking obesity with cardiovascular disease (2006, positive): “, and selectively suppresses endothelial cell apoptosi”
- Adipocytokines in Obesity and Metabolic Disease (2014, positive): “In addition, adiponectin confers vascular-protective activities by suppressing the apoptosis of endothelial cell (Kobayashi et al. 2004).”