Adiponectin and adiponectin receptors.

By Takashi Kadowaki, Toshimasa Yamauchi. Endocrine reviews, 2005

2,737 citations recorded by the source corpus.

Subfields: Endocrine and Autonomic Systems, Epidemiology, Physiology

View Paper: https://www.semanticscholar.org/paper/3c7ecf77247dcbb374922f43303f87cce4fc6947

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In Endocrine and Autonomic Systems

1. Jianping Ye
2. Sushil Kumar Jain
3. G. Frühbeck

In Epidemiology

1. Jianping Ye
2. J. Bastard
3. Sushil Kumar Jain
4. Prasenjit Manna
5. B. Fève
6. G. Frühbeck

In Physiology

1. Jianping Ye
2. Sushil Kumar Jain
3. G. Frühbeck

Citations in the corpus

• Adipokines: the missing link between insulin resistance and obesity. (2008, background): “Adiponectin also affects hepatic glucose production by ecreasing the mRNA expression of two essential gluconeoenesis enzymes: phosphoenolpyruvate carboxykinase; and lucose-6-phosphatase [45].”
• Obesity, Oxidative Stress, Adipose Tissue Dysfunction, and the Associated Health Risks: Causes and Therapeutic Strategies (2015, background): “It was observed that highmolecular-weight adiponectin may have a more insulinsensitizing effect compared to its monomeric form.(266) Like leptin, adiponectin also enhances insulin sensitivity through the activation of AMPK.”
• Endocrine regulation of energy metabolism by the skeleton. (2007, background): “Accordingly, expression of the adiponectin target genes Acyl-CoA Oxidase, Ppara, and Ucp2 was increased in Esp / mice (Figure 2N; Kadowaki and Yamauchi, 2005).”
• Psoriasis and systemic inflammatory diseases: potential mechanistic links between skin disease and co-morbid conditions. (2010, background): “Adiponectin also affects hepatic glucose production by decreasing the mRNA expression of two essential gluconeogenesis enzymes: phosphoenolpyruvate carboxykinase and glucose-6-phosphatase (Kadowaki and Yamauchi, 2005).”
• Intracellular signalling pathways activated by leptin. (2006, background): “…channels and peptides both in the central nervous system as well as in the periphery, such as resistin [162,163], ghrelin [164], adiponectin [165], peptide YY 3 − 36 [166], visfatin [167], vaspin (visceral adipose tissue-derived serine protease inhibitor) [168], endocannabinoids [169,170],…”
• Cardiac remodeling in obesity. (2008, background): “The relevance of this model stems from the fact that levels of adiponectin are invariably reduced in animals and humans with obesity (161).”
• Adipose tissue dysfunction in obesity, diabetes, and vascular diseases. (2008, background): “and augmenting energy expenditure in vitro, presumably by enhanced uncoupling of adenosine triphosphate (ATP) generation in mitochondria.(25) In an insulin-resistant mouse model administration of adiponectin has been shown to ameliorate hyperglycaemia and hyperinsulinaemia.”
• Biochemistry of adipose tissue: an endocrine organ (2013, background): “The biological effects of these receptors depend not only on blood concentrations of adiponectin but also tissue specificity [17, 25].”
• Metabolic Syndrome and Insulin Resistance: Underlying Causes and Modification by Exercise Training (2013, neutral): “Adiponectin represents the most abundant protein secreted by adipose tissue (212) and adipose transcript as well as circulating levels of this protein are reduced in humans and in rodent models of obesity and T2D, as reviewed in references (27, 293, 323, 497, 645).”
• Hypoxia is a potential risk factor for chronic inflammation and adiponectin reduction in adipose tissue of ob/ob and dietary obese mice. (2007, background): “A reduction in plasma adiponectin is widely observed in obesity and type 2 diabetes (22).”