Reward-related fMRI activation of dopaminergic midbrain is associated with enhanced hippocampus-dependent long-term memory formation

By B. Wittmann, B. Schott, S. Guderian, Julietta U. Frey, Hans-Jochen Heinze, Emrah Düzel. Neuron, 2005

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Subfields: Cellular and Molecular Neuroscience, Cognitive Neuroscience

View Paper: https://www.semanticscholar.org/paper/0497a44551c8d3bb52cad0299ebd59c2071fc791

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Citations in the corpus

Distributed Neural Representation of Expected Value (2005, background): “Other experiments have also demonstrated ventral–striatal activation during anticipation of rewards using noncontingent tasks (O’Doherty et al., 2002; Ramnani et al., 2004; Wittmann et al., 2005).”
Functional magnetic resonance imaging of reward prediction (2005, background): “A second study found that anticipation of monetary reward improved incidental memory for reward cue features and this improvement was related to midbrain and ventral striatal modulation of medial temporal lobe activation during encoding [ 41 ].”
Integrating Memories in the Human Brain: Hippocampal–Midbrain Encoding of Overlapping Events (2008, background): “, 2003; Otmakhova and Lisman, 1996); indeed, both midbrain activation (Wittmann et al., 2005) and interaction between hippocampus and midbrain (Adcock et al.”
Selectivity in Postencoding Connectivity with High-Level Visual Cortex Is Associated with Reward-Motivated Memory (2017, background): “…support a novel mechanism whereby postencoding processes contribute to the selection of high-reward representations for memory stabilization that is independent from previously demonstrated encoding-related activations (Wittmann et al., 2005; Adcock et al., 2006; Wolosin et al., 2012).”
Reward-motivated learning: mesolimbic activation precedes memory formation. (2006, background): “, 1998), and line drawings (Wittmann et al., 2005) correlates with later memory for those stimuli.”
The mesolimbic dopamine reward circuit in depression. (2006, background): “…innervation from VTA dopamine neurons, where dopaminergic transmission has been shown to profoundly affect the functioning of these regions in electrophysiological and behavioral paradigms (e.g., see Goldman-Rakic et al 2000; Louilot and Besso 2000; Pezze and Feldon 2004; Wittmann et al 2005).”
ReviewThe Hippocampal-VTA Loop : Controlling the Entry of Information into Long-Term Memory (2005, neutral): “i further supported by recent fMRI data showing that r VTA and substantia nigra midbrain regions in humans w can be activated by reward or novelty (Schott et al., 2004; Uzakov et al., 2004; Wittmann et al., 2005), similar c to the findings in rats and primates.”
Post-learning hippocampal dynamics promote preferential retention of rewarding events (2016, background): “Consistent with these models, functional magnetic resonance imaging (fMRI) studies in humans have shown that reward motivation enhances memory encoding and is associated with increased activity in, and interactions between, the SN/VTA and the hippocampus (Adcock et al., 2006; Murty and Adcock, 2014;”
Burst timing-dependent plasticity of NMDA receptor-mediated transmission in midbrain dopamine neurons: A putative cellular substrate for reward learning (2009, neutral): “, 2006; Schultz, 1998), DA does play an important role in memory encoding in the hippocampus (Adcock et al., 2006; Gasbarri et al., 1996; Hersi et al., 1995; Li et al., 2003; Lisman and Grace, 2005; Wittmann et al., 2005) and amygdala (Bissiere et al.”
Neuroplasticity subserving motor skill learning (2011, neutral): “A reward-related enhancement of long-term memory has been demonstrated for other forms of memory as well (Wittmann et al., 2011) and is linked with fMRI activation in the striatum, ventral tegmental area, and hippocampus (Wittmann et al., 2005; Adcock et al., 2006).”
Dysfunction of ventral striatal reward prediction in schizophrenia (2006, background): “…to the nucleus accumbens, other limbic and prefrontal brain areas, such as the orbitofrontal and anterior cingulate cortex, amygdala, hippocampus , insula, thalamus, striatum, and dopaminergic midbrain (O'Doherty et al., 2002; Kirsch et al., 2003; Ernst et al., 2004; Wittmann et al., 2005).”
The Reward Circuit: Linking Primate Anatomy and Human Imaging (2010, background): “In addition, midbrain increases in activation have been reported in response to reward-predicting cues (Adcock et al , 2006; Wittmann et al , 2005), and this activation, in concert with medial temporal lobe activation, predicts subsequent enhancements in memory for associated stimuli.”