Ian Tomlinson

Molecular Biology · 2002–2021

A researcher in the Science corpus: 14 papers; trusts 3 researchers and is trusted by 0 researchers here, as inferred from the citation graph.

Subfields

• Molecular Biology — 89 citations into it
• Cancer Research — 55 citations into it
• Oncology — 23 citations into it

Whom Ian Tomlinson trusts overall

Their strongest outbound trust, strongest first, inferred from their citations.

1. G. Semenza
2. Julian P. T. Higgins

Who trusts Ian Tomlinson overall

1. Ralph J. Deberardinis

Papers from Ian Tomlinson's perspective

Ordered by how strongly the researchers Ian Tomlinson trusts endorse each paper. Same corpus, a different order for every researcher.

1. Targeting HIF-1 for cancer therapy (Nature Reviews. Cancer)
2. Mutations in SDHD, a mitochondrial complex II gene, in hereditary paraganglioma. (Science)
3. Hypoxia — a key regulatory factor in tumour growth (Nature Reviews. Cancer)
4. Why do cancers have high aerobic glycolysis? (Nature Reviews. Cancer)
5. Oxygen sensing by HIF hydroxylases (Nature reviews. Molecular cell biology)
6. Akt Stimulates Aerobic Glycolysis in Cancer Cells (Cancer Research)
7. Succinate links TCA cycle dysfunction to oncogenesis by inhibiting HIF-alpha prolyl hydroxylase. (Cancer Cell)
8. HIF-1 and tumor progression: pathophysiology and therapeutics. (Trends in Molecular Medicine)
9. Quantifying heterogeneity in a meta‐analysis (Statistics in Medicine)
10. HIF overexpression correlates with biallelic loss of fumarate hydratase in renal cancer: novel role of fumarate in regulation of HIF stability. (Cancer Cell)

Their papers

• Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer (2002) — 1,426 citations
• CCAT2, a novel noncoding RNA mapping to 8q24, underlies metastatic progression and chromosomal instability in colon cancer (2013) — 620 citations
• Replication stress links structural and numerical cancer chromosomal instability (2013) — 840 citations
• Breast Cancer Risk Genes — Association Analysis in More than 113,000 Women (2021) — 858 citations
• Deep learning for prediction of colorectal cancer outcome: a discovery and validation study. (2020) — 492 citations
• Large-scale genotyping identifies 41 new loci associated with breast cancer risk (2013) — 1,135 citations
• The interleukin-6 receptor as a target for prevention of coronary heart disease: a mendelian randomisation analysis (2012) — 1,018 citations
• Germline mutations in the proof-reading domains of POLE and POLD1 predispose to colorectal adenomas and carcinomas (2012) — 943 citations
• Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21 (2008) — 643 citations
• Meta-analysis of genome-wide association data identifies four new susceptibility loci for colorectal cancer (2008) — 603 citations
• A genome-wide association scan of tag SNPs identifies a susceptibility variant for colorectal cancer at 8q24.21 (2007) — 837 citations
• Accumulation of Krebs cycle intermediates and over-expression of HIF1alpha in tumours which result from germline FH and SDH mutations. (2005) — 892 citations
• Mitochondrial tumour suppressors: a genetic and biochemical update (2005) — 647 citations
• Multiple colorectal adenomas, classic adenomatous polyposis, and germ-line mutations in MYH. (2003) — 926 citations