H. Jhoti
Computational Chemistry & Drug Discovery · 2002–2016
A researcher in the Science corpus: 7 papers; trusts 1 researcher and is trusted by 8 researchers here, as inferred from the citation graph.
Subfields
- Computational Chemistry & Drug Discovery — 13 citations into it; #215 of 425 by trust here, #215 by citations
Whom H. Jhoti trusts overall
Their strongest outbound trust, strongest first, inferred from their citations.
Who trusts H. Jhoti overall
Papers from H. Jhoti's perspective
Ordered by how strongly the researchers H. Jhoti trusts endorse each paper. Same corpus, a different order for every researcher.
- Ligand efficiency: a useful metric for lead selection. (Drug Discovery Today)
- The Protein Data Bank.
- Increased Energy Expenditure, Decreased Adiposity, and Tissue-Specific Insulin Sensitivity in Protein-Tyrosine Phosphatase 1B-Deficient Mice (Molecular and Cellular Biology)
- Drug discovery: a historical perspective. (Science)
- Crystal structure of the human β2 adrenergic G-protein-coupled receptor
- Functionality maps of binding sites: A multiple copy simultaneous search method
- The role of ligand efficiency metrics in drug discovery
- Structure of a β1-adrenergic G protein-coupled receptor (Nature)
- An inhibitor of Bcl-2 family proteins induces regression of solid tumours (Nature)
- Protein structure--based drug design.
Their papers
- High-throughput crystallography for lead discovery in drug design (2002) — 503 citations
- A 'rule of three' for fragment-based lead discovery? (2003) — 1,177 citations
- Oxidation state of the active-site cysteine in protein tyrosine phosphatase 1B (2003) — 638 citations
- The 'rule of three' for fragment-based drug discovery: where are we now? (2013) — 271 citations
- Twenty years on: the impact of fragments on drug discovery (2016) — 798 citations
- Crystal Structures of Human Cytochrome P450 3A4 Bound to Metyrapone and Progesterone (2004) — 791 citations
- Crystal structure of human cytochrome P450 2C9 with bound warfarin (2003) — 773 citations