Protein structure--based drug design.

By Peter John Whittle, Tom L. Blundell. 1994

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

1. Jinbo Xu
2. Sheng Wang
3. Jianzhu Ma
4. Jian Peng
5. Chris Abell
6. H. Jhoti
7. Badri Adhikari
8. Tom L. Blundell

Citations in the corpus

• Protein Secondary Structure Prediction Using Deep Convolutional Neural Fields (2015, methodology): “Our method differs from Zhou’s deep learning method (denoted as ICML2014)36 in the following aspects: (1) our method places only input features in a visible layer and treats the SS labels as hidden states while Zhou’s method places both the input features and SS labels in a visible layer; (2) our me”
• High-throughput crystallography for lead discovery in drug design (2002, background): “Knowledge of the three-dimensional structures of target proteins provides a starting point for structure-based approaches to drug design by defining the topographies of the complementary surfaces of ligands and their protein target”