C. Sawyers
Molecular Biology · 2001–2024
A researcher in the Science corpus: 40 papers; trusts 4 researchers and is trusted by 28 researchers here, as inferred from the citation graph.
Subfields
- Molecular Biology — 237 citations into it; #2,435 of 17,773 by trust here, #770 by citations
- Pulmonary and Respiratory Medicine — 168 citations into it; #167 of 770 by trust here, #18 by citations
- Oncology — 120 citations into it; #303 of 1,698 by trust here, #543 by citations
- Cancer Research — 102 citations into it; #879 of 1,780 by trust here, #264 by citations
- Pathology and Forensic Medicine — 42 citations into it
Whom C. Sawyers trusts overall
Their strongest outbound trust, strongest first, inferred from their citations.
Who trusts C. Sawyers overall
- A. Arora
- E. Scholar
- H. Shigematsu
- Berthold Huppertz
- Brian J. Druker
- Paul Geeleher
- William Pao
- Vardhman K. Rakyan
- Philip A Watson
- D. Altieri
Papers from C. Sawyers's perspective
Ordered by how strongly the researchers C. Sawyers trusts endorse each paper. Same corpus, a different order for every researcher.
- Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR (Proceedings of the National Academy of Sciences of the United States of America)
- Molecular portraits of human breast tumours (Nature)
- Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors. (New England Journal of Medicine)
- Hematologic and cytogenetic responses to imatinib mesylate in chronic myelogenous leukemia. (New England Journal of Medicine)
- Phosphorylation and Regulation of Akt/PKB by the Rictor-mTOR Complex (Science)
- mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways (Nature Medicine)
- S6K1−/−/S6K2−/− Mice Exhibit Perinatal Lethality and Rapamycin-Sensitive 5′-Terminal Oligopyrimidine mRNA Translation and Reveal a Mitogen-Activated Protein Kinase-Dependent S6 Kinase Pathway (Molecular and Cellular Biology)
- KRAS Mutations and Primary Resistance of Lung Adenocarcinomas to Gefitinib or Erlotinib (PLoS Medicine)
- Hypoxia-inducible factor determines sensitivity to inhibitors of mTOR in kidney cancer (Nature Medicine)
- Bronchioloalveolar pathologic subtype and smoking history predict sensitivity to gefitinib in advanced non-small-cell lung cancer. (Journal of Clinical Oncology)
Their papers
- Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR (2001) — 1,019 citations
- Hypoxia-inducible factor determines sensitivity to inhibitors of mTOR in kidney cancer (2006) — 640 citations
- An inhibitor of mTOR reduces neoplasia and normalizes p70/S6 kinase activity in Pten+/− mice (2001) — 620 citations
- Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia. (2001) — 5,221 citations
- The phosphatidylinositol 3-Kinase–AKT pathway in human cancer (2002) — 6,297 citations
- Targeted cancer therapy (2004) — 1,078 citations
- Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors. (2005) — 1,471 citations
- Myc-driven murine prostate cancer shares molecular features with human prostate tumors. (2003) — 813 citations
- Reciprocal feedback regulation of PI3K and androgen receptor signaling in PTEN-deficient prostate cancer. (2011) — 1,201 citations
- Rb1 and Trp53 cooperate to suppress prostate cancer lineage plasticity, metastasis, and antiandrogen resistance (2017) — 939 citations
- Antitumor Activity of Rapamycin in a Phase I Trial for Patients with Recurrent PTEN-Deficient Glioblastoma (2008) — 597 citations
- The cancer biomarker problem (2008) — 958 citations
- Assessment of TROP2, CEACAM5 and DLL3 in metastatic prostate cancer: Expression landscape and molecular correlates (2024)
- Genomic correlates of clinical outcome in advanced prostate cancer (2019) — 1,212 citations
- The long tail of oncogenic drivers in prostate cancer (2018) — 754 citations
- SOX2 promotes lineage plasticity and antiandrogen resistance in TP53- and RB1-deficient prostate cancer (2017) — 945 citations
- Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer (2016) — 1,457 citations
- Integrative clinical genomics of advanced prostate cancer (2015) — 3,214 citations
- Emerging Mechanisms of Resistance to Androgen Receptor Inhibitors in Prostate Cancer (2015) — 1,370 citations
- Identification of multipotent luminal progenitor cells in human prostate organoid cultures (2014) — 680 citations