Xiaodong Wang
Cell · 2000–2014
A researcher in the Science corpus: 17 papers; trusts 0 researchers and is trusted by 35 researchers here, as inferred from the citation graph.
Whom Xiaodong Wang trusts overall
Their strongest outbound trust, strongest first, inferred from their citations.
Who trusts Xiaodong Wang overall
Papers from Xiaodong Wang's perspective
Ordered by how strongly the researchers Xiaodong Wang trusts endorse each paper. Same corpus, a different order for every researcher.
- Proapoptotic BAX and BAK: A Requisite Gateway to Mitochondrial Dysfunction and Death (Science)
- Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. (Cell)
- A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis (Nature)
- Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics. (Cancer Cell)
- Structural and biochemical basis of apoptotic activation by Smac/DIABLO (Nature)
- BH3-only proteins that bind pro-survival Bcl-2 family members fail to induce apoptosis in the absence of Bax and Bak. (Genes & Development)
- Endonuclease G is an apoptotic DNase when released from mitochondria (Nature)
- Improved methods for building protein models in electron density maps and the location of errors in these models.
- tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c. (Genes & Development)
- The Bcl2 family: regulators of the cellular life-or-death switch (Nature Reviews. Cancer)
Their papers
- R2D2, a Bridge Between the Initiation and Effector Steps of the Drosophila RNAi Pathway (2003) — 803 citations
- Mixed lineage kinase domain-like protein mediates necrosis signaling downstream of RIP3 kinase. (2012) — 2,549 citations
- Endonuclease G is an apoptotic DNase when released from mitochondria (2001) — 1,875 citations
- The mitochondrial phosphatase PGAM5 functions at the convergence point of multiple necrotic death pathways. (2012) — 954 citations
- Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition. (2000) — 3,661 citations
- A Small Molecule Smac Mimic Potentiates TRAIL- and TNFα-Mediated Cell Death (2004) — 616 citations
- Structural basis of IAP recognition by Smac/DIABLO (2000) — 880 citations
- Mixed lineage kinase domain-like protein MLKL causes necrotic membrane disruption upon phosphorylation by RIP3. (2014) — 1,483 citations
- Structural and biochemical basis of apoptotic activation by Smac/DIABLO (2000) — 899 citations
- Mule/ARF-BP1, a BH3-only E3 ubiquitin ligase, catalyzes the polyubiquitination of Mcl-1 and regulates apoptosis. (2005) — 871 citations
- Elimination of Mcl-1 is required for the initiation of apoptosis following ultraviolet irradiation. (2003) — 628 citations
- Argonaute2 cleaves the anti-guide strand of siRNA during RISC activation. (2005) — 851 citations
- Receptor interacting protein kinase-3 determines cellular necrotic response to TNF-alpha. (2009) — 1,879 citations
- Cytochrome C-mediated apoptosis. (2003) — 1,432 citations
- Autocrine TNFalpha signaling renders human cancer cells susceptible to Smac-mimetic-induced apoptosis. (2007) — 606 citations
- Toll-like receptors activate programmed necrosis in macrophages through a receptor-interacting kinase-3–mediated pathway (2011) — 701 citations
- Hsp90 cochaperone Aha1 downregulation rescues misfolding of CFTR in cystic fibrosis. (2006) — 622 citations