K. Wittrup
Molecular Biology · 2000–2019
A researcher in the Science corpus: 5 papers; trusts 1 researcher and is trusted by 8 researchers here, as inferred from the citation graph.
Subfields
- Molecular Biology — 13 citations into it; #4,677 of 17,773 by trust here, #7,842 by citations
Whom K. Wittrup trusts overall
Their strongest outbound trust, strongest first, inferred from their citations.
Who trusts K. Wittrup overall
Papers from K. Wittrup's perspective
Ordered by how strongly the researchers K. Wittrup trusts endorse each paper. Same corpus, a different order for every researcher.
- De novo protein design: fully automated sequence selection.
- De novo design of the hydrophobic cores of proteins
- IMGT/V-QUEST: the highly customized and integrated system for IG and TR standardized V-J and V-D-J sequence analysis
- RosettaAntibody: antibody variable region homology modeling server
- Design of a Novel Globular Protein Fold with Atomic-Level Accuracy
- Addressing polyspecificity of antibodies selected from an in vitro yeast presentation system: a FACS-based, high-throughput selection and analytical tool.
- Isolating and engineering human antibodies using yeast surface display
- Direct activation of STING in the tumor microenvironment leads to potent and systemic tumor regression and immunity
- The intrinsic contributions of tyrosine, serine, glycine and arginine to the affinity and specificity of antibodies.
- Spatiotemporal dynamics of intratumoral immune cells reveal the immune landscape in human cancer. (Immunity)
Their papers
- Computational design of antibody-affinity improvement beyond in vivo maturation (2007) — 360 citations
- Substantial energetic improvement with minimal structural perturbation in a high affinity mutant antibody. (2004) — 138 citations
- Directed evolution of antibody fragments with monovalent femtomolar antigen-binding affinity. (2000) — 689 citations
- Anchoring of intratumorally administered cytokines to collagen safely potentiates systemic cancer immunotherapy (2019) — 182 citations
- Nonspecificity in a nonimmune human scFv repertoire (2017) — 26 citations