Neural stem cells in the adult mammalian forebrain: a relatively quiescent subpopulation of subependymal cells.

By C. Morshead, B. Reynolds, Constance G. Craig, M. McBurney, W. Staines, D. Morassutti, S. Weiss, D. Kooy. 1994

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Citations in the corpus

Adult Neurogenesis in the Mammalian Brain: Significant Answers and Significant Questions (2011, background): “…on marker expression and antimitotic agent treatment suggests that putative adult neural stem cells are mostly quiescent (Doetsch et al., 1999; Morshead et al., 1994; Seri et al., 2001); thus classic lineage-tracing tools, such as BrdU and retroviruses , which require cell division, are not…”
High Levels of Id1 Expression Define B1 Type Adult Neural Stem Cells (2009, background): “The cell-cycle time of an endogenous NSC may be up to 28 days in vivo (Morshead et al., 1994).”
Neurogenesis in the adult brain: new strategies for central nervous system diseases. (2004, background): “Indeed, at least a subpopulation of proliferating cells in the SVZ express the EGF-receptor (88, 89), and a nullmutation for the EGF-receptor ligand TGFα (56) leads to significantly decreased stem/progenitor cell proliferation within the SVZ.”
Multipotential nestin-positive stem cells isolated from adult pancreatic islets differentiate ex vivo into pancreatic endocrine, exocrine, and hepatic phenotypes. (2001, methodology): “GLP-1 levels varied from 15 to 67 pg/ml. NIP cells were pretreated with activin-A and HGF or betacellulin.”
Neural stem and progenitor cells in nestin‐GFP transgenic mice (2004, background): “When cultured in vitro, they are capable of forming clonally derived groups of cells (neurospheres; Reynolds and Weiss, 1992; Morshead et al., 1994).”
Maturation and Death of Adult-Born Olfactory Bulb Granule Neurons: Role of Olfaction (2002, background): “This is consistent with evidence that very few long-term renewing stem cells get labeled in the SVZ after proliferation marker injections (Morshead et al., 1994; Doetsch et al., 1997).”
Presenilin 1 mutants impair the self-renewal and differentiation of adult murine SVZ-neuronal progenitors via cell autonomous mechanisms involving Notch signaling (2010, methodology): “NPCs that give rise to neurospheres were cultured from dissected subependymal tissue, including minimal regions of ependyma and striatum, in serum-free medium supplemented with the mitogens, EGF and b-FGF as described earlier (Morshead et al., 1994; Chiasson et al., 1999).”
Adult neurogenesis and neural stem cells of the central nervous system in mammals (2002, background): “, 1992); in the SVZ of mouse (Lois and Alvarez-Buylla, 1993; Morshead et al., 1994), rat (Palmer et al.”
In vivo clonal analysis reveals self-renewing and multipotent adult neural stem cell characteristics (2011, unknown): “Because neural stem cells in the adult brain are believed to be largely quiescent (Doetsch et al., 1999; Morshead et al., 1994; Seri et al., 2001), BrdU- and retrovirus-based labeling approaches, which require active cell division, are not effective for labeling these cells in vivo.”
Origin of Oligodendrocytes in the Subventricular Zone of the Adult Brain (2006, background): “Adult neural stem cells grown from the adult SVZ as neurospheres can generate oligodendrocytes (Morshead et al., 1994; Gritti et al., 1996; Weiss et al., 1996; Doetsch et al., 1999; Pluchino et al., 2003).”