Neural stem and progenitor cells in nestin‐GFP transgenic mice

By J. Mignone, V. Kukekov, Ann-Shyn Chiang, D. Steindler, G. Enikolopov. The Journal of comparative neurology, 2004

721 citations recorded by the source corpus.

Subfields: Developmental Neuroscience, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/5ad4ed630fb9501b91da361fdfd39733f78ec000

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In Developmental Neuroscience

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Citations in the corpus

In vivo fate analysis reveals the multipotent and self-renewal capacities of Sox2+ neural stem cells in the adult hippocampus. (2007, background): “…for radial glial cells and/or NSCs. Sox2-GFP cells colocalized with radial glial cell markers including NESTIN (Fukuda et al., 2003; Kronenberg et al., 2003; Mignone et al., 2004), GFAP (Seri et al., 2004), and BLBP (Anthony et al., 2004), particularly in their radial processes (Figures 1D–1F).”
Type‐2 cells as link between glial and neuronal lineage in adult hippocampal neurogenesis (2006, background): “1E and 2C,C0).”
Single-cell RNA-seq with Waterfall Reveals Molecular Cascades underlying Adult Neurogenesis (2015, background): “In the hippocampal dentate SGZ of adult Nes-GFP mice (Mignone et al., 2004), AldocGFP precursors were almost exclusively PCNA qNSCs, with very few PCNA active NSCs (aNSCs) or IPCs (Figure 3B).”
Visualization and genetic manipulation of adult neurogenesis using transgenic mice (2011, background): “In the SVZ and RMS, nestin-labeled cells co-label with proteins that are associated with Type B, C and A cells (Doetsch et al., 1997; Mignone et al., 2004).”
Single-Cell Profiling and SCOPE-Seq Reveal Lineage Dynamics of Adult Ventricular-Subventricular Zone Neurogenesis and NOTUM as a Key Regulator (2020, positive): “This result was consistent with the flow cytometric quantification showing stronger NOTUM surface labeling on cells with higher epidermal growth factor (EGF)-ligand binding affinity (Codega et al., 2014) compared with Nestin-CFP + EGF binding − cells, containing V-SVZ qNSCs (unpaired t test, p 0.0”
Microglia shape adult hippocampal neurogenesis through apoptosis-coupled phagocytosis (2010, methodology): “NPCs were visualized in nestin-GFP transgenic mice, which express GFP under the nestin promoter and regulatory elements (Mignone et al., 2004).”
Bone marrow CD169+ macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche (2011, methodology): “…Laboratory), CX3CR1/GFP (Jung et al., 2000; gift from D. Littman, New York University, New York, NY), CD169-DTR (Miyake et al., 2007), Nes-Gfp (Mignone et al., 2004), Nes-CreERT2 (Balordi and Fishell, 2007), iDTR (C57BL/6-Gt[R OSA]26Sortm1[HBEGF]Awai/J; Buch et al., 2005), IL-10/ (Berg et…”
Developmental profile of neurogenesis in prenatal human hippocampus: An immunohistochemical study (2014, background): “Thereinto, nestin is a member of the intermediate filament protein family and this marker is widely used to indicate neural stem/progenitor cells in study (Lillien, 1998; Mignone et al., 2004).”
The endocannabinoid system drives neural progenitor proliferation (2005, neutral): “Materials Nestin-GFP transgenic mice (18) were kindly donated by G.”
Leptin Receptor-expressing mesenchymal stromal cells represent the main source of bone formed by adult bone marrow (2014, neutral): “…2010), Rosa26-loxp-stop-loxp-EYFP (Srinivas et al., 2001), Rosa26-loxp-stop-loxp-iDTR (Buch et al., 2005), NG2-creERTM (Zhu et al., 2011), Wnt-1-cre (Danielian and McMahon, 1996), Nestin-GFP (Mignone et al., 2004), Nestin-creER (Balordi and Fishell, 2007), Mx-1-cre (Kühn et al., 1995), and Col2.”
Gremlin 1 Identifies a Skeletal Stem Cell with Bone, Cartilage, and Reticular Stromal Potential (2015, methodology): “We used the following lines: Nes-GFP (Mignone et al., 2004), Nes-CreERT2 (Dranovsky et al.”
Coupled Proliferation and Apoptosis Maintain the Rapid Turnover of Microglia in the Adult Brain (2017, methodology): “We analyzed Nestin-GFP mice as an optimal reporter mouse for the expression of nestin (Mignone et al., 2004), and although we showed the previously reported expression in pericytes (Figures 4A–4C), neural stem cells (Figure 4B), and oligodendrocyte precursor cells (Figures 4A and 4C) (Mignone et al.”
Division-Coupled Astrocytic Differentiation and Age-Related Depletion of Neural Stem Cells in the Adult Hippocampus (2011, methodology): “Neural stem and progenitor cells can be readily identified in reporter mouse lines (NestinGFP or Nestin-CFPnuc) in which the Nestin gene regulatory elements drive the expression of fluorescent proteins (FPs) (Encinas and Enikolopov, 2008; Encinas et al., 2006; Enikolopov and Overstreet-Wadiche, 2008”