Paradigm shifts in Alzheimer's disease and other neurodegenerative disorders: The emerging role of oligomeric assemblies

By M. Kirkitadze, G. Bitan, David B. Teplow. Journal of Neuroscience Research, 2002

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Structure–neurotoxicity relationships of amyloid β-protein oligomers (2009, background): “(1996) Morphology and toxicity of A -(1-42) dimer derived from”
The Alzheimer's Disease-Associated Amyloid β-Protein Is an Antimicrobial Peptide (2010, unknown): “We have observed that LL-37 exhibits striking similarities to Ab, including a propensity to form cytotoxic soluble oligomers [15,16,17,18] and insoluble fibrils that demonstrate congophilia and birefringence [19], two classical histochemical properties of tinctorial amyloid.”
Synaptic Targeting by Alzheimer's-Related Amyloid β Oligomers (2004, background): “The data provide a new molecular mechanism to support the emerging hypothesis that early AD memory loss is an oligomer-induced synapse failure, independent of neuron death and amyloid fibrils (Lambert et al., 1998; Klein et al., 2001; Hardy and Selkoe, 2002; Kirkitadze et al., 2002; Walsh and Selkoe”